Bharat Book Bureau

This report details the complete range of products and technologies in spine surgery, including the surgical management of spine disorders, diseases and trauma, with treatments including use of grafts, demineralized bone, fusion, stabilization, disc replacement, nucleus replacement, vertebroplasty, kyphoplasty, imaging, minimally invasive surgical technologies, energy-based therapies and biologics. The report details current clinical and technology developments in the huge and rapidly growing spine surgery technologies worldwide market, with data on products in development and on the market; market size and forecast; competitor market shares; competitor profiles; and market opportunity.

This report is a detailed market and technology assessment and forecast of the products and technologies in the management of diseases and disorders of the spine. The report describes diseases and disorders of the spine, encompassing congenital disorders, inflammatory and infectious diseases; degenerative diseases; herniations, stenoses, myelopathies and other “mechanical” disorders of the spine; spinal trauma; tumors of the spine; and others. The report characterizes the patient populations, their current clinical management, and trends in clinical management as new techniques and technologies are expected to be developed and emerge. The report details the currently available products and technologies, and manufacturer offerings. The report details products and technologies under development and markets for each in spine surgery. The report provides a current and forecast assessment of the worldwide markets for these technologies, with geographic segmentation by U.S. & Canada, European Union (detailing France, United Kingdom, Germany, Italy and Spain), Japan and Rest of World. The report provides emphasis on the market impact of new technologies through the coming decade, profiling nearly 100 active companies in this industry, with comprehensive detail on key companies, providing data on their current products, current market position and products under development.

Table of Contents:

Executive Summary
Non-fusion products
Disc arthroplasty (total disc replacement)
Nuclear arthroplasty
European Union
Asia-Pacific
Rest of World
Selected company-related events
Medtronic
LDR Spine
Synthes Spine
Disc Motion Technologies
Spine Structure
Products and technologies
CMS, carriers reverse decision on artificial discs
Cost effectiveness

Section 1:          The Spine: Structure, Disorders, Treatment
1.1         Overview: Spine Structure
1.2         Diseases and disorders of the spine
1.2.1             Congenital Disorders
1.2.2             Inflammatory and Infectious Diseases of the Spine
1.2.3             Degenerative Diseases of the Spine
1.2.4             Mechanical Disorders of the Spine
1.2.5             Spinal Trauma
1.2.6             Tumors of the Spine
1.3         Spine management
1.3.1             Clinical: the SPORT Study
1.3.2             Diagnostic studies
1.3.3             Surgical procedures of the spine
1.3.4             Minimally Invasive Procedures
1.3.5             Minimally Invasive Bone Grafting Procedures
1.3.6             Acupuncture for treatment of chronic low back pain

Section 2:          Products and Technologies
2.1         Bone grafts and bone graft substitutes
2.2         Demineralized bone matrix (DBM)
2.2.1             Particle based DBM
2.2.2             Biomimetic matrix bone substitute
2.2.3             Bone morphogenic proteins (BMPs)
2.3         Spinal fusion and fixation products and technologies
2.3.1             Spine surgery instrumentation
2.3.2             Cervical fusion devices
2.3.3             Interbody fusion devices
2.3.4             Posterior dynamic stabilization systems
2.4         Non-fusion products and technologies
2.4.1             Disc arthroplasty
2.4.2             Nuclear arthroplasty and nuclear disc prostheses
2.4.3             Facet repair and replacement
2.5         Vertebroplasty and kyphoplasty
2.5.1             Vertebral compression fracture treatment technologies
2.6         Advances in spinal image-guided surgery
2.6.1             Medtronic’s StealthStation
2.6.2             GE Healthcare’s Fluoro-Spine
2.6.3             Elekta’s Axesse system
2.6.4             Zimmer’s ORTHOsoft Navitrack® FluoroSpine® System
2.7         Products and technologies for minimally invasive spinal surgery
2.7.1             ArthroCare’s spineWand
2.7.2             Medtronic’s MAST™ portfolio
2.7.3             NuVasive’s Maximum Access Surgery (MAS)
2.7.4             Abbott Spine’s Harmony Retractor
2.7.5             Globus transforaminal TDR device
2.8         Energy-based therapies
2.8.1             Bone growth stimulators
2.8.2             Intradiscal Electrothermal Therapy (IDET)
2.9         Biologics

Section 3:          Market Size, Forecast and Competitor Shares
3.1         Global market size, forecast and competitor shares
3.2         USA & Canada
3.2.1             Bone grafts and bone graft substitutes
3.2.2             Spinal fusion and fixation products
3.2.3             Non-fusion products
3.2.4             Vertebroplasty and Kyphoplasty
3.2.5             Interspinous process spacers (ISP)
3.2.6             Computer assisted image guided surgery products
3.3         European Union
3.3.1             United Kingdom
3.3.2             France
3.3.3             Germany
3.3.4             Italy
3.3.5             Spinal fusion and fixation products
3.3.6             Non-fusion products
3.3.7             Total disc replacement
3.3.8             Nucleus replacement
3.3.9             Interspinous process spacers (ISPs)
3.3.10           Kyphoplasty
3.3.11           Image Guided Surgery Products Market
3.4         Asia-Pacific
3.4.1             Spinal fusion and fixation products
3.4.2             Non-fusion products
3.4.3             Image guided surgery products
3.5         Rest of World

Section 4:          Regulatory, Cost and Reimbursement Issues
4.1         Regulatory Issues Associated with Spine Treatments, Materials and Methods
4.1.1             Regulatory issues regarding off-label usage
4.1.2             Changes to European Device Safety Regulations
4.1.3             NICE and dynamic stabilization procedures
4.2         Reimbursement Developments
4.2.1             CMS, carriers reverse decision on artificial discs
4.2.2             CMS reverses stand on two spinal fusion procedures
4.2.3             ArthroCare and DiscoCare
4.2.4             Bone growth factor reimbursement issues
4.2.5             CMS investigates Thermal Intradiscal Therapy
4.2.6             CMS announces new ICD-9-CM spinal procedure codes
4.2.7             Wellmark and energy-based treatments
4.3         Cost effectiveness

Section 5:          Company Profiles
5.1         Abbott Spine
5.2         AlloSource
5.3         Alphatec Holdings, Inc.
5.4         Altiva Corporation
5.5         Anulex Technologies, Inc.
5.6         ApaTech
5.7         Applied Spine Technologies
5.8         ArthroCare Corporation
5.9         A-Spine Holding Group Corporation
5.10       Axial Biotech
5.11       AxioMed Spine Corporation
5.12       B. Braun/Aesculap, Inc.
5.13       BioAssets Development Corporation
5.14       Biomet
5.15       Biorthex, Inc.
5.16       Blackstone Medical, Inc
5.17       BrainLAB
5.18       Cardinal Health
5.19       Cervitech
5.20       Changzhou Kanghui
5.21       Co.Don AG
5.22       CoLigne AG
5.23       Cook Group
5.24       CoreSpine Technologies LLC
5.25       Corin Group
5.26       Cortek, Inc
5.27       Cryolife, Inc.
5.28       Cyberkinetics Neurotechnology Systems
5.29       Cytori Therapeutics
5.30       DePuy Spine/J&J
5.31       Disc Dynamics
5.32       Disc Motion Technologies
5.33       Encore Medical Corporation / DJO Surgical (ReAble Therapeutics)
5.34       Facet Solutions
5.35       Fixano (Small Bone Innovations)
5.36       GE Healthcare
5.37       Gentis, Inc
5.38       Globus Medical
5.39       GMReis
5.40       HydroCision
5.41       [Innovative Spinal Technologies — ceased operations January 2009]
5.42       Integra LifeSciences
5.43       Integra Radionics
5.44       Interpore Cross
5.45       Interventional Spine
5.46       Invibio
5.47       LDR Holding Corporation
5.48       LifeNet Health, Inc.
5.49       Mazor Surgical Technologies Ltd
5.50       Medtronic, Inc
5.51       Medtronic Sofamor Danek
5.52       Medtronic Surgical Navigation
5.53       Mekanika, Inc.
5.54       Merck & Co., Inc.
5.55       MiMedx
5.56       Misonix
5.57       MTF (Musculoskeletal Transplant Foundation)
5.58       NPS Pharmaceuticals
5.59       N Spine, Inc. (Synthes)
5.60       NuVasive, Inc.
5.61       Ortho Development Corporation
5.62       Orthofix International, N.V.
5.63       OrthoVita
5.64       Osiris Therapeutics
5.65       Osteotech, Inc.
5.66       Ortosintese
5.67       Paradigm Spine, LLC
5.68       Pitkar
5.69       Praxim
5.70       Ranier Technology Limited
5.71       Raymedica, Inc.
5.72       Regeneration Technologies, Inc
5.73       Scient’X
5.74       SeaSpine, Inc.
5.75       Sharma Surgical
5.76       Small Bone Innovations, LLC
5.77       Smart Disc
5.78       Smith & Nephew
5.79       SpinalMotion
5.80       SpineMedica Corporation
5.81       Spineology
5.82       SpineOvations
5.83       SpineVision Inc
5.84       Spine Wave, Inc.
5.85       Stryker Corporation
5.86       Stryker Instruments
5.87       Stryker Spine
5.88       Synthes Spine Solutions
5.89       Theken Spine
5.90       TranS1, Inc.
5.91       Trimedyne, Inc.
5.92       Ulrich Medical GmbH
5.93       Valleylab
5.94       Vertebron Inc.
5.95       Waston Medical
5.96       Wright Medical Technology
5.97       X-spine Systems, Inc.
5.98       Zimmer Spine
Appendix:  Company Directory

List of Exhibits

Exhibit ES-1: Total Global Spine Surgery Market, 2008-2017
Exhibit ES-2: Total Global Spine Surgery Market, 2008-2017
Exhibit ES-3: Global Spine Surgery Market by Segment, in USD Terms
Exhibit ES-4: Global Spine Surgery Market by Percentage and Segments, 2008
Exhibit ES-5: Major Spine Market Segments, 2008-2017
Exhibit ES-6: Key Factors Driving Growth in the Global Spine Surgery Market
Exhibit ES-7: Global Spine Surgery Market Shares, 2008
Exhibit ES-8: US & Canadian Market for Spine Surgery Devices
Exhibit ES-9: US Company Market Shares for Spine Surgery Devices, 2008
Exhibit ES-10: Total Global Spine Surgery Market, by Region, 2008
Exhibit ES-11: Total EU Spine Surgery Market, 2008-2017
Exhibit ES-12: Total EU Spine Surgery Market, 2008-2017
Exhibit ES-13: EU Spine Surgery Market Shares, 2008
Exhibit ES-14: Asia-Pacific: Total Spine Surgery Market, 2008-2017
Exhibit ES-15: Asia-Pacific: Total Spine Surgery Market, 2008-2017
Exhibit ES-16: Asia-Pacific: Spine Surgery Market Shares, 2008
Exhibit ES-17: Rest of World Spine Surgery Market Shares, 2008
Exhibit ES-18: ROW, Spine Surgery Markets, 2008-2017
Exhibit ES-19: Lateral and Posterior Views of the Spine
Exhibit ES-20: Human Spine Structure Showing Vertebrae, Intervertebral Discs, and Spinal Cord
Exhibit ES-21: US Census figures and projections, ages 65 and up, 1900-2050.
Exhibit ES-22: Number & Percentage of U.S. Population over Age 65, 1910–2050
Exhibit ES-23: Mechanical Disorders of the Spine
Exhibit ES-24: Start-up companies and areas of interest
Exhibit ES-25: CPT spinal fusion codes now allowed by CMS
Exhibit ES-26: Summary of CMS Medicare cost data

Exhibit 1-1: Lateral and Posterior Views of the Spine
Exhibit 1-2: Human Spine Structure Showing Vertebrae, Intervertebral Discs, and Spinal Cord
Exhibit 1-3: Components of the Human Spine
Exhibit 1-4: US Census figures and projections, ages 65 and up, 1900-2050.
Exhibit 1-5: Number & Percentage of U.S. Population over Age 65, 1910–2050
Exhibit 1-6: Congenital Disorders of the Spine
Exhibit 1-7: Inflammatory and Infectious Diseases of the Spine
Exhibit 1-8: Degenerative Diseases of the Spine
Exhibit 1-9: Estimated Annual Number of Fractures Due to Osteoporosis in the U.S. (Total: Over 1.5 Million)
Exhibit 1-10: Mechanical Disorders of the Spine
Exhibit 1-11: Location, Effects, and Incidence of Major Lumbar Disc Herniations
Exhibit 1-12: Clinical Features—Radiculopathy by Spinal Level
Exhibit 1-13: Causes of Trauma to Spinal Regions
Exhibit 1-14: Tumors of the Spine
Exhibit 1-15: Traditional (“Open”) Spinal Procedures
Exhibit 1-16: Estimated Number of Spinal Fusion Procedures Performed in the U.S., 2005–2015
Exhibit 1-17: Minimally Invasive Spinal Procedures

Exhibit 2-1: Spinal Allografts: Vendors and Products
Exhibit 2-2: Hydroxyapatite Bone Substitutes: Vendors, Products
Exhibit 2-3: Bone growth stimulatory proteins, peptides and devices
Exhibit 2-4: Fusion instrumentation companies
Exhibit 2-5: Developers of Interspinous Process Spacers
Exhibit 2-6: Developers of Total Disc Replacements
Exhibit 2-7: Artificial Cervical Discs Currently in US Clinical Trials
Exhibit 2-8: Artificial Cervical Discs Currently Available in the EU
Exhibit 2-9: Total disc replacement devices
Exhibit 2-10: Developers of Prosthetic Disc Nuclei
Exhibit 2-11: Nucleus replacement implants
Exhibit 2-12: Current nucleus arthroplasty motion preservation IDE pilot studies
Exhibit 2-13: Bone growth stimulatory proteins, peptides and devices
Exhibit 2-14: Cellular therapies: manufacturers and product
Exhibit 2-15: Other start-up companies and areas of interest

Exhibit 3-1: Total Global Spine Surgery Market, 2008-2017
Exhibit 3-2: Total Global Spine Surgery Market, 2008-2017
Exhibit 3-3: Global Spine Surgery Market by Segment, in USD Terms
Exhibit 3-4: Global Spine Surgery Market by Percentage and Segments, 2008
Exhibit 3-5: Key Factors Driving Growth in the Global Spine Surgery Market
Exhibit 3-6: Major Spine Market Segments, 2008-2017
Exhibit 3-7: Global Spine Surgery Market Shares, 2008
Exhibit 3-8: US & Canadian Market for Spine Surgery Devices
Exhibit 3-9: US & Canadian Market for Spine Surgery Devices
Exhibit 3-10: US Company Market Shares for Spine Surgery Devices, 2008
Exhibit 3-11: Usage of Bone Grafts and Bone Graft Substitutes in Spinal Fusion Procedures (excluding BMPs)
Exhibit 3-12: US Market for Bone Graft Substitutes
Exhibit 3-13: US Market for Spine-Related Orthobiologics, 2008-2017
Exhibit 3-14: US & Canadian Market for Spinal Fusion and Fixation Devices
Exhibit 3-14B:  US & Canadian Spinal Fusion Procedures by Segment (Cervical, Lumbar, Thoracic), 2008-2017
Exhibit 3-15: Number of Spinal Fusions
Exhibit 3-16: US & Canadian Market for Spinal Fusion and Fixation Devices
Exhibit 3-17: US Market Shares, Spinal Fusion and Fixation Devices, 2008
Exhibit 3-18: US Market Shares, Spinal Fusion and Fixation Devices, 2008
Exhibit 3-19 Total US Non-Fusion Device Market
Exhibit 3-20: Total US Non-Fusion Device Market
Exhibit 3-21: US Annulus Repair Market, 2009-2015
Exhibit 3-22: US Annulus Repair Market, 2009-2015
Exhibit 3-23: Total Market for Disc Arthroplasty (Cervical Plus Thoracolumbar)
Exhibit 3-24: US Market for Cervical Disc Replacement
Exhibit 3-25: US Market for Cervical Disc Replacement
Exhibit 3-26: US Market for Thoracolumbar Disc Replacement
Exhibit 3-27: US Market for Thoracolumbar Disc Replacement
Exhibit 3-28: US & Canadian Markets for Nuclear Arthroplasty
Exhibit 3-29: US Market for Nucleus Replacement
Exhibit 3-30: Total US Market for Vertebroplasty and Kyphoplasty
Exhibit 3-31: US Market for Vertebroplasty
Exhibit 3-32: US Market for Vertebroplasty
Exhibit 3-33: US Market for Kyphoplasty
Exhibit 3-34: US Market for Kyphoplasty
Exhibit 3-35: 2008 US Market Shares, Combined Vertebroplasty/Kyphoplasty
Exhibit 3-36: US Interspinous Process Spacers Market, 2008-2017
Exhibit 3-37: US Interspinous Process Spacers Market, 2008-2017
Exhibit 3-38: US Market for Image Guided Surgery Devices
Exhibit 3-39: US Market for Image Guided Surgery Devices
Exhibit 3-40: US Competitor Shares, Image Guided Surgery Devices, 2008
Exhibit 3-41: Total Global Spine Surgery Market, by Region, 2008
Exhibit 3-42: Total EU Spine Surgery Market, 2008-2017
Exhibit 3-43: Total EU Spine Surgery Market, 2008-2017
Exhibit 3-44: EU Spine Surgery Market by Segment, in USD
Exhibit 3-45: EU Spine Surgery Market by Percentage and Segments, 2008
Exhibit 3-46: EU Spine Surgery Market Shares, 2008
Exhibit 3-47: United Kingdom: Total Spine Surgery Market, 2008-2017
Exhibit 3-48: United Kingdom: Total Spine Surgery Market, 2008-2017
Exhibit 3-49: UK: Total Spine Surgery Market Shares, 2008
Exhibit 3-50: France: Total Spine Surgery Market, 2008-2017
Exhibit 3-51: France: Total Spine Surgery Market, 2008-2017
Exhibit 3-52: France: Total Spine Surgery Market Shares, 2008
Exhibit 3-53: Germany: Total Spine Surgery Market, 2008-2017
Exhibit 3-54: Germany: Total Spine Surgery Market, 2008-2017
Exhibit 3-55: Germany: Total Spine Surgery Market Shares, 2008
Exhibit 3-56: Italy: Total Spine Surgery Market, 2008-2017
Exhibit 3-57: Italy: Total Spine Surgery Market, 2008-2017
Exhibit 3-58: Italy: Total Spine Surgery Market Shares, 2008
Exhibit 3-59: Total EU Spine Fusion and Fixation Market, 2008-2017
Exhibit 3-60: Total EU Spine Fusion and Fixation Market, 2008-2017
Exhibit 3-61: United Kingdom: Spinal Fusion and Fixation Market, 2008-2017
Exhibit 3-62: France: Spinal Fusion and Fixation Market, 2008-2017
Exhibit 3-63: Germany: Spinal Fusion and Fixation Market, 2008-2017
Exhibit 3-64: Italy: Spine Fusion and Fixation Market, 2008-2017
Exhibit 3-65: Total EU Non-Fusion Market, 2008-2017
Exhibit 3-66: Total EU Non-Fusion Market, 2008-2017
Exhibit 3-67: United Kingdom: Non-fusion Products Market, 2008-2017
Exhibit 3-68: France: Total Non-Fusion Products Market, 2008-2017
Exhibit 3-69: Germany: Total Non-fusion Market, 2008-2017
Exhibit 3-70: Italy: Non-fusion Products Market, 2008-2017
Exhibit 3-71: Total EU Disc Replacement Market, 2008-2017
Exhibit 3-72: Total EU Disc Replacement Market, 2008-2017
Exhibit 3-73: United Kingdom: Total Disc Replacement Market, 2008-2017
Exhibit 3-74: France: Total Disc Replacement Market, 2008-2017
Exhibit 3-75: Germany: Total Disc Replacement Market, 2008-2017
Exhibit 3-76: Italy: Total Disc Replacement Market, 2008-2017
Exhibit 3-77: Total EU Nucleus Replacement Market, 2008-2017
Exhibit 3-78: Total EU Nucleus Replacement Market, 2008-2017
Exhibit 3-79: United Kingdom: Nucleus Replacement Market, 2008-2017
Exhibit 3-80: France: Nucleus Replacement Market, 2008-2017
Exhibit 3-81: Germany: Nucleus Replacement Market, 2008-2017
Exhibit 3-82: Italy: Nucleus Replacement Market, 2008-2017
Exhibit 3-83: Total EU Interspinous Process Spacers (ISPs) Market, 2008-2017
Exhibit 3-84: Total EU Interspinous Process Spacers (ISPs) Market, 2008-2017
Exhibit 3-85: United Kingdom: Interspinous Process Spacers Market, 2008-2017
Exhibit 3-86: France: Interspinous Process Spacers Market, 2008-2017
Exhibit 3-87: Germany: Total Spine Surgery Market, 2008-2017
Exhibit 3-88: Italy: Interspinous Process Spacers Market, 2008-2017
Exhibit 3-89: Total EU Kyphoplasty Market, 2008-2017
Exhibit 3-90: Total EU Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-91: United Kingdom: Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-92: France: Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-93: Germany: Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-94: Italy: Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-95: EU Market for Computer Assisted Image Guided Surgery Products, 2008-2017
Exhibit 3-96: United Kingdom: Image Guided Surgery Market, 2008-2017
Exhibit 3-97: France: Image Guided Surgery Market, 2008-2017
Exhibit 3-98: Germany: Image Guided Surgery Market, 2008-2017
Exhibit 3-99: Italy: Image Guided Surgery Market, 2008-2017
Exhibit 3-100: Asia-Pacific: Total Spine Surgery Market, 2008-2017
Exhibit 3-101: Asia-Pacific: Total Spine Surgery Market, 2008-2017
Exhibit 3-102: Asia-Pacific: Spine Surgery Market Shares, 2008
Exhibit 3-103: Asia-Pacific: Spinal Fusion and Fixation Market, 2008-2017
Exhibit 3-104: Asia-Pacific: Spinal Fusion and Fixation Market, 2008-2017
Exhibit 3-105: Asia-Pacific: Non-fusion Products Market, 2008-2017
Exhibit 3-106: Asia-Pacific: Non-fusion Products Market, 2008-2017
Exhibit 3-107: Asia-Pacific: Spinal Fusion vs. Non Fusion Markets, 2008 vs. 2017
Exhibit 3-108: Asia-Pacific: Total Disc Replacement Market, 2008-2017
Exhibit 3-109: Asia-Pacific: Total Disc Replacement Market, 2008-2017
Exhibit 3-110: Asia-Pacific: Nucleus Replacement Market, 2008-2017
Exhibit 3-111: Asia-Pacific: Nucleus Replacement Market, 2008-2017
Exhibit 3-112: Asia-Pacific: Interspinous Processes Market, 2008-2017
Exhibit 3-113: Asia-Pacific: Interspinous Processes Market, 2008-2017
Exhibit 3-114: Asia-Pacific: Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-115: Asia-Pacific: Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-116: Asia-Pacific: Image Guided Surgery Market, 2008-2017
Exhibit 3-117: Asia-Pacific: Image Guided Surgery Market, 2008-2017
Exhibit 3-118: Rest of World Spine Surgery Market Shares, 2008
Exhibit 3-119: ROW, Spine Surgery Markets, 2008-2017
Exhibit 3-120: ROW, Spine Surgery Markets, 2008-2017
Exhibit 3-121: ROW: Fusion and Fixation Market, 2008-2017
Exhibit 3-122: ROW: Fusion and Fixation Market, 2008-2017
Exhibit 3-123: ROW: Non-Fusion Market, 2008-2017
Exhibit 3-124: ROW: Total Disc Replacement Market, 2008-2017
Exhibit 3-125: ROW: Nucleus Replacement Market, 2008-2017
Exhibit 3-126: ROW: Interspinous Process Spacers Market, 2008-2017
Exhibit 3-127: ROW: Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-128: ROW: Image-Guided Surgery Market, 2008-2017

Exhibit 4-1: CPT spinal fusion codes now allowed by CMS
Exhibit 4-2: BCBSNC coverage of bone morphogenetic protein
Exhibit 4-3: New CMS codes for spinal motion preservation
Exhibit 4-4: Summary of CMS Medicare cost data

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This report details the complete range of sealants & glues technologies used in traumatic, surgical and other wound closure, from tapes, sutures and staples to hemostats, fibrin sealants/glues and medical adhesives. The report details current clinical and technology developments in this huge and rapidly growing worldwide market, with data on products in development and on the market; market size and forecast; competitor market shares; competitor profiles; and market opportunity.

This report is a market and technology assessment and forecast of surgical sealants, glues, hemostasis, other wound closure and anti-adhesion. The report details the current and emerging products, technologies and markets involved in wound closure and sealing using sutures and staples, tapes, hemostats, fibrin and sealant products, medical adhesives and products to prevent surgical adhesions. The report provides a worldwide current and annual forecast to 2013 of the markets for these technologies, with particular emphasis on the market impact of new technologies through the coming decade. The report provides specific forecasts and shares of the worldwide market by segment for the U.S., Europe (United Kingdom, German, France, Italy, BeNeLux), Latin America, Japan and Rest of World.

The report provides background data on the surgical, disease and traumatic wound patient populations targeted by current technologies and those under development, and the current clinical practices in the management of these patients, including the dynamics among the various clinical specialties or subspecialties vying for patient population and facilitating or limiting the growth of technologies.

The report establishes the current worldwide market size for major technology segments as a baseline for and projecting growth in the market over a ten-year forecast. The report also assesses and projects the composition of the market as technologies gain or lose relative market performance over this period.

For more information kindly visit
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This report details the complete range of products and technologies in spine surgery, including the surgical management of spine disorders, diseases and trauma, with treatments including use of grafts, demineralized bone, fusion, stabilization, disc replacement, nucleus replacement, vertebroplasty, kyphoplasty, imaging, minimally invasive surgical technologies, energy-based therapies and biologics. The report details current clinical and technology developments in the huge and rapidly growing spine surgery technologies worldwide market, with data on products in development and on the market; market size and forecast; competitor market shares; competitor profiles; and market opportunity.

This report is a detailed market and technology assessment and forecast of the products and technologies in the management of diseases and disorders of the spine. The report describes diseases and disorders of the spine, encompassing congenital disorders, inflammatory and infectious diseases; degenerative diseases; herniations, stenoses, myelopathies and other “mechanical” disorders of the spine; spinal trauma; tumors of the spine; and others. The report characterizes the patient populations, their current clinical management, and trends in clinical management as new techniques and technologies are expected to be developed and emerge. The report details the currently available products and technologies, and manufacturer offerings. The report details products and technologies under development and markets for each in spine surgery. The report provides a current and forecast assessment of the worldwide markets for these technologies, with geographic segmentation by U.S. & Canada, European Union (detailing France, United Kingdom, Germany, Italy and Spain), Japan and Rest of World. The report provides emphasis on the market impact of new technologies through the coming decade, profiling nearly 100 active companies in this industry, with comprehensive detail on key companies, providing data on their current products, current market position and products under development.

Table of Contents:

Executive Summary
Non-fusion products
Disc arthroplasty (total disc replacement)
Nuclear arthroplasty
European Union
Asia-Pacific
Rest of World
Selected company-related events
Medtronic
LDR Spine
Synthes Spine
Disc Motion Technologies
Spine Structure
Products and technologies
CMS, carriers reverse decision on artificial discs
Cost effectiveness

Section 1:          The Spine: Structure, Disorders, Treatment
1.1         Overview: Spine Structure
1.2         Diseases and disorders of the spine
1.2.1             Congenital Disorders
1.2.2             Inflammatory and Infectious Diseases of the Spine
1.2.3             Degenerative Diseases of the Spine
1.2.4             Mechanical Disorders of the Spine
1.2.5             Spinal Trauma
1.2.6             Tumors of the Spine
1.3         Spine management
1.3.1             Clinical: the SPORT Study
1.3.2             Diagnostic studies
1.3.3             Surgical procedures of the spine
1.3.4             Minimally Invasive Procedures
1.3.5             Minimally Invasive Bone Grafting Procedures
1.3.6             Acupuncture for treatment of chronic low back pain

Section 2:          Products and Technologies
2.1         Bone grafts and bone graft substitutes
2.2         Demineralized bone matrix (DBM)
2.2.1             Particle based DBM
2.2.2             Biomimetic matrix bone substitute
2.2.3             Bone morphogenic proteins (BMPs)
2.3         Spinal fusion and fixation products and technologies
2.3.1             Spine surgery instrumentation
2.3.2             Cervical fusion devices
2.3.3             Interbody fusion devices
2.3.4             Posterior dynamic stabilization systems
2.4         Non-fusion products and technologies
2.4.1             Disc arthroplasty
2.4.2             Nuclear arthroplasty and nuclear disc prostheses
2.4.3             Facet repair and replacement
2.5         Vertebroplasty and kyphoplasty
2.5.1             Vertebral compression fracture treatment technologies
2.6         Advances in spinal image-guided surgery
2.6.1             Medtronic’s StealthStation
2.6.2             GE Healthcare’s Fluoro-Spine
2.6.3             Elekta’s Axesse system
2.6.4             Zimmer’s ORTHOsoft Navitrack® FluoroSpine® System
2.7         Products and technologies for minimally invasive spinal surgery
2.7.1             ArthroCare’s spineWand
2.7.2             Medtronic’s MAST™ portfolio
2.7.3             NuVasive’s Maximum Access Surgery (MAS)
2.7.4             Abbott Spine’s Harmony Retractor
2.7.5             Globus transforaminal TDR device
2.8         Energy-based therapies
2.8.1             Bone growth stimulators
2.8.2             Intradiscal Electrothermal Therapy (IDET)
2.9         Biologics

Section 3:          Market Size, Forecast and Competitor Shares
3.1         Global market size, forecast and competitor shares
3.2         USA & Canada
3.2.1             Bone grafts and bone graft substitutes
3.2.2             Spinal fusion and fixation products
3.2.3             Non-fusion products
3.2.4             Vertebroplasty and Kyphoplasty
3.2.5             Interspinous process spacers (ISP)
3.2.6             Computer assisted image guided surgery products
3.3         European Union
3.3.1             United Kingdom
3.3.2             France
3.3.3             Germany
3.3.4             Italy
3.3.5             Spinal fusion and fixation products
3.3.6             Non-fusion products
3.3.7             Total disc replacement
3.3.8             Nucleus replacement
3.3.9             Interspinous process spacers (ISPs)
3.3.10           Kyphoplasty
3.3.11           Image Guided Surgery Products Market
3.4         Asia-Pacific
3.4.1             Spinal fusion and fixation products
3.4.2             Non-fusion products
3.4.3             Image guided surgery products
3.5         Rest of World

Section 4:          Regulatory, Cost and Reimbursement Issues
4.1         Regulatory Issues Associated with Spine Treatments, Materials and Methods
4.1.1             Regulatory issues regarding off-label usage
4.1.2             Changes to European Device Safety Regulations
4.1.3             NICE and dynamic stabilization procedures
4.2         Reimbursement Developments
4.2.1             CMS, carriers reverse decision on artificial discs
4.2.2             CMS reverses stand on two spinal fusion procedures
4.2.3             ArthroCare and DiscoCare
4.2.4             Bone growth factor reimbursement issues
4.2.5             CMS investigates Thermal Intradiscal Therapy
4.2.6             CMS announces new ICD-9-CM spinal procedure codes
4.2.7             Wellmark and energy-based treatments
4.3         Cost effectiveness

Section 5:          Company Profiles
5.1         Abbott Spine
5.2         AlloSource
5.3         Alphatec Holdings, Inc.
5.4         Altiva Corporation
5.5         Anulex Technologies, Inc.
5.6         ApaTech
5.7         Applied Spine Technologies
5.8         ArthroCare Corporation
5.9         A-Spine Holding Group Corporation
5.10       Axial Biotech
5.11       AxioMed Spine Corporation
5.12       B. Braun/Aesculap, Inc.
5.13       BioAssets Development Corporation
5.14       Biomet
5.15       Biorthex, Inc.
5.16       Blackstone Medical, Inc
5.17       BrainLAB
5.18       Cardinal Health
5.19       Cervitech
5.20       Changzhou Kanghui
5.21       Co.Don AG
5.22       CoLigne AG
5.23       Cook Group
5.24       CoreSpine Technologies LLC
5.25       Corin Group
5.26       Cortek, Inc
5.27       Cryolife, Inc.
5.28       Cyberkinetics Neurotechnology Systems
5.29       Cytori Therapeutics
5.30       DePuy Spine/J&J
5.31       Disc Dynamics
5.32       Disc Motion Technologies
5.33       Encore Medical Corporation / DJO Surgical (ReAble Therapeutics)
5.34       Facet Solutions
5.35       Fixano (Small Bone Innovations)
5.36       GE Healthcare
5.37       Gentis, Inc
5.38       Globus Medical
5.39       GMReis
5.40       HydroCision
5.41       [Innovative Spinal Technologies — ceased operations January 2009]
5.42       Integra LifeSciences
5.43       Integra Radionics
5.44       Interpore Cross
5.45       Interventional Spine
5.46       Invibio
5.47       LDR Holding Corporation
5.48       LifeNet Health, Inc.
5.49       Mazor Surgical Technologies Ltd
5.50       Medtronic, Inc
5.51       Medtronic Sofamor Danek
5.52       Medtronic Surgical Navigation
5.53       Mekanika, Inc.
5.54       Merck & Co., Inc.
5.55       MiMedx
5.56       Misonix
5.57       MTF (Musculoskeletal Transplant Foundation)
5.58       NPS Pharmaceuticals
5.59       N Spine, Inc. (Synthes)
5.60       NuVasive, Inc.
5.61       Ortho Development Corporation
5.62       Orthofix International, N.V.
5.63       OrthoVita
5.64       Osiris Therapeutics
5.65       Osteotech, Inc.
5.66       Ortosintese
5.67       Paradigm Spine, LLC
5.68       Pitkar
5.69       Praxim
5.70       Ranier Technology Limited
5.71       Raymedica, Inc.
5.72       Regeneration Technologies, Inc
5.73       Scient’X
5.74       SeaSpine, Inc.
5.75       Sharma Surgical
5.76       Small Bone Innovations, LLC
5.77       Smart Disc
5.78       Smith & Nephew
5.79       SpinalMotion
5.80       SpineMedica Corporation
5.81       Spineology
5.82       SpineOvations
5.83       SpineVision Inc
5.84       Spine Wave, Inc.
5.85       Stryker Corporation
5.86       Stryker Instruments
5.87       Stryker Spine
5.88       Synthes Spine Solutions
5.89       Theken Spine
5.90       TranS1, Inc.
5.91       Trimedyne, Inc.
5.92       Ulrich Medical GmbH
5.93       Valleylab
5.94       Vertebron Inc.
5.95       Waston Medical
5.96       Wright Medical Technology
5.97       X-spine Systems, Inc.
5.98       Zimmer Spine
Appendix:  Company Directory

List of Exhibits

Exhibit ES-1: Total Global Spine Surgery Market, 2008-2017
Exhibit ES-2: Total Global Spine Surgery Market, 2008-2017
Exhibit ES-3: Global Spine Surgery Market by Segment, in USD Terms
Exhibit ES-4: Global Spine Surgery Market by Percentage and Segments, 2008
Exhibit ES-5: Major Spine Market Segments, 2008-2017
Exhibit ES-6: Key Factors Driving Growth in the Global Spine Surgery Market
Exhibit ES-7: Global Spine Surgery Market Shares, 2008
Exhibit ES-8: US & Canadian Market for Spine Surgery Devices
Exhibit ES-9: US Company Market Shares for Spine Surgery Devices, 2008
Exhibit ES-10: Total Global Spine Surgery Market, by Region, 2008
Exhibit ES-11: Total EU Spine Surgery Market, 2008-2017
Exhibit ES-12: Total EU Spine Surgery Market, 2008-2017
Exhibit ES-13: EU Spine Surgery Market Shares, 2008
Exhibit ES-14: Asia-Pacific: Total Spine Surgery Market, 2008-2017
Exhibit ES-15: Asia-Pacific: Total Spine Surgery Market, 2008-2017
Exhibit ES-16: Asia-Pacific: Spine Surgery Market Shares, 2008
Exhibit ES-17: Rest of World Spine Surgery Market Shares, 2008
Exhibit ES-18: ROW, Spine Surgery Markets, 2008-2017
Exhibit ES-19: Lateral and Posterior Views of the Spine
Exhibit ES-20: Human Spine Structure Showing Vertebrae, Intervertebral Discs, and Spinal Cord
Exhibit ES-21: US Census figures and projections, ages 65 and up, 1900-2050.
Exhibit ES-22: Number & Percentage of U.S. Population over Age 65, 1910–2050
Exhibit ES-23: Mechanical Disorders of the Spine
Exhibit ES-24: Start-up companies and areas of interest
Exhibit ES-25: CPT spinal fusion codes now allowed by CMS
Exhibit ES-26: Summary of CMS Medicare cost data

Exhibit 1-1: Lateral and Posterior Views of the Spine
Exhibit 1-2: Human Spine Structure Showing Vertebrae, Intervertebral Discs, and Spinal Cord
Exhibit 1-3: Components of the Human Spine
Exhibit 1-4: US Census figures and projections, ages 65 and up, 1900-2050.
Exhibit 1-5: Number & Percentage of U.S. Population over Age 65, 1910–2050
Exhibit 1-6: Congenital Disorders of the Spine
Exhibit 1-7: Inflammatory and Infectious Diseases of the Spine
Exhibit 1-8: Degenerative Diseases of the Spine
Exhibit 1-9: Estimated Annual Number of Fractures Due to Osteoporosis in the U.S. (Total: Over 1.5 Million)
Exhibit 1-10: Mechanical Disorders of the Spine
Exhibit 1-11: Location, Effects, and Incidence of Major Lumbar Disc Herniations
Exhibit 1-12: Clinical Features—Radiculopathy by Spinal Level
Exhibit 1-13: Causes of Trauma to Spinal Regions
Exhibit 1-14: Tumors of the Spine
Exhibit 1-15: Traditional (“Open”) Spinal Procedures
Exhibit 1-16: Estimated Number of Spinal Fusion Procedures Performed in the U.S., 2005–2015
Exhibit 1-17: Minimally Invasive Spinal Procedures

Exhibit 2-1: Spinal Allografts: Vendors and Products
Exhibit 2-2: Hydroxyapatite Bone Substitutes: Vendors, Products
Exhibit 2-3: Bone growth stimulatory proteins, peptides and devices
Exhibit 2-4: Fusion instrumentation companies
Exhibit 2-5: Developers of Interspinous Process Spacers
Exhibit 2-6: Developers of Total Disc Replacements
Exhibit 2-7: Artificial Cervical Discs Currently in US Clinical Trials
Exhibit 2-8: Artificial Cervical Discs Currently Available in the EU
Exhibit 2-9: Total disc replacement devices
Exhibit 2-10: Developers of Prosthetic Disc Nuclei
Exhibit 2-11: Nucleus replacement implants
Exhibit 2-12: Current nucleus arthroplasty motion preservation IDE pilot studies
Exhibit 2-13: Bone growth stimulatory proteins, peptides and devices
Exhibit 2-14: Cellular therapies: manufacturers and product
Exhibit 2-15: Other start-up companies and areas of interest

Exhibit 3-1: Total Global Spine Surgery Market, 2008-2017
Exhibit 3-2: Total Global Spine Surgery Market, 2008-2017
Exhibit 3-3: Global Spine Surgery Market by Segment, in USD Terms
Exhibit 3-4: Global Spine Surgery Market by Percentage and Segments, 2008
Exhibit 3-5: Key Factors Driving Growth in the Global Spine Surgery Market
Exhibit 3-6: Major Spine Market Segments, 2008-2017
Exhibit 3-7: Global Spine Surgery Market Shares, 2008
Exhibit 3-8: US & Canadian Market for Spine Surgery Devices
Exhibit 3-9: US & Canadian Market for Spine Surgery Devices
Exhibit 3-10: US Company Market Shares for Spine Surgery Devices, 2008
Exhibit 3-11: Usage of Bone Grafts and Bone Graft Substitutes in Spinal Fusion Procedures (excluding BMPs)
Exhibit 3-12: US Market for Bone Graft Substitutes
Exhibit 3-13: US Market for Spine-Related Orthobiologics, 2008-2017
Exhibit 3-14: US & Canadian Market for Spinal Fusion and Fixation Devices
Exhibit 3-14B:  US & Canadian Spinal Fusion Procedures by Segment (Cervical, Lumbar, Thoracic), 2008-2017
Exhibit 3-15: Number of Spinal Fusions
Exhibit 3-16: US & Canadian Market for Spinal Fusion and Fixation Devices
Exhibit 3-17: US Market Shares, Spinal Fusion and Fixation Devices, 2008
Exhibit 3-18: US Market Shares, Spinal Fusion and Fixation Devices, 2008
Exhibit 3-19 Total US Non-Fusion Device Market
Exhibit 3-20: Total US Non-Fusion Device Market
Exhibit 3-21: US Annulus Repair Market, 2009-2015
Exhibit 3-22: US Annulus Repair Market, 2009-2015
Exhibit 3-23: Total Market for Disc Arthroplasty (Cervical Plus Thoracolumbar)
Exhibit 3-24: US Market for Cervical Disc Replacement
Exhibit 3-25: US Market for Cervical Disc Replacement
Exhibit 3-26: US Market for Thoracolumbar Disc Replacement
Exhibit 3-27: US Market for Thoracolumbar Disc Replacement
Exhibit 3-28: US & Canadian Markets for Nuclear Arthroplasty
Exhibit 3-29: US Market for Nucleus Replacement
Exhibit 3-30: Total US Market for Vertebroplasty and Kyphoplasty
Exhibit 3-31: US Market for Vertebroplasty
Exhibit 3-32: US Market for Vertebroplasty
Exhibit 3-33: US Market for Kyphoplasty
Exhibit 3-34: US Market for Kyphoplasty
Exhibit 3-35: 2008 US Market Shares, Combined Vertebroplasty/Kyphoplasty
Exhibit 3-36: US Interspinous Process Spacers Market, 2008-2017
Exhibit 3-37: US Interspinous Process Spacers Market, 2008-2017
Exhibit 3-38: US Market for Image Guided Surgery Devices
Exhibit 3-39: US Market for Image Guided Surgery Devices
Exhibit 3-40: US Competitor Shares, Image Guided Surgery Devices, 2008
Exhibit 3-41: Total Global Spine Surgery Market, by Region, 2008
Exhibit 3-42: Total EU Spine Surgery Market, 2008-2017
Exhibit 3-43: Total EU Spine Surgery Market, 2008-2017
Exhibit 3-44: EU Spine Surgery Market by Segment, in USD
Exhibit 3-45: EU Spine Surgery Market by Percentage and Segments, 2008
Exhibit 3-46: EU Spine Surgery Market Shares, 2008
Exhibit 3-47: United Kingdom: Total Spine Surgery Market, 2008-2017
Exhibit 3-48: United Kingdom: Total Spine Surgery Market, 2008-2017
Exhibit 3-49: UK: Total Spine Surgery Market Shares, 2008
Exhibit 3-50: France: Total Spine Surgery Market, 2008-2017
Exhibit 3-51: France: Total Spine Surgery Market, 2008-2017
Exhibit 3-52: France: Total Spine Surgery Market Shares, 2008
Exhibit 3-53: Germany: Total Spine Surgery Market, 2008-2017
Exhibit 3-54: Germany: Total Spine Surgery Market, 2008-2017
Exhibit 3-55: Germany: Total Spine Surgery Market Shares, 2008
Exhibit 3-56: Italy: Total Spine Surgery Market, 2008-2017
Exhibit 3-57: Italy: Total Spine Surgery Market, 2008-2017
Exhibit 3-58: Italy: Total Spine Surgery Market Shares, 2008
Exhibit 3-59: Total EU Spine Fusion and Fixation Market, 2008-2017
Exhibit 3-60: Total EU Spine Fusion and Fixation Market, 2008-2017
Exhibit 3-61: United Kingdom: Spinal Fusion and Fixation Market, 2008-2017
Exhibit 3-62: France: Spinal Fusion and Fixation Market, 2008-2017
Exhibit 3-63: Germany: Spinal Fusion and Fixation Market, 2008-2017
Exhibit 3-64: Italy: Spine Fusion and Fixation Market, 2008-2017
Exhibit 3-65: Total EU Non-Fusion Market, 2008-2017
Exhibit 3-66: Total EU Non-Fusion Market, 2008-2017
Exhibit 3-67: United Kingdom: Non-fusion Products Market, 2008-2017
Exhibit 3-68: France: Total Non-Fusion Products Market, 2008-2017
Exhibit 3-69: Germany: Total Non-fusion Market, 2008-2017
Exhibit 3-70: Italy: Non-fusion Products Market, 2008-2017
Exhibit 3-71: Total EU Disc Replacement Market, 2008-2017
Exhibit 3-72: Total EU Disc Replacement Market, 2008-2017
Exhibit 3-73: United Kingdom: Total Disc Replacement Market, 2008-2017
Exhibit 3-74: France: Total Disc Replacement Market, 2008-2017
Exhibit 3-75: Germany: Total Disc Replacement Market, 2008-2017
Exhibit 3-76: Italy: Total Disc Replacement Market, 2008-2017
Exhibit 3-77: Total EU Nucleus Replacement Market, 2008-2017
Exhibit 3-78: Total EU Nucleus Replacement Market, 2008-2017
Exhibit 3-79: United Kingdom: Nucleus Replacement Market, 2008-2017
Exhibit 3-80: France: Nucleus Replacement Market, 2008-2017
Exhibit 3-81: Germany: Nucleus Replacement Market, 2008-2017
Exhibit 3-82: Italy: Nucleus Replacement Market, 2008-2017
Exhibit 3-83: Total EU Interspinous Process Spacers (ISPs) Market, 2008-2017
Exhibit 3-84: Total EU Interspinous Process Spacers (ISPs) Market, 2008-2017
Exhibit 3-85: United Kingdom: Interspinous Process Spacers Market, 2008-2017
Exhibit 3-86: France: Interspinous Process Spacers Market, 2008-2017
Exhibit 3-87: Germany: Total Spine Surgery Market, 2008-2017
Exhibit 3-88: Italy: Interspinous Process Spacers Market, 2008-2017
Exhibit 3-89: Total EU Kyphoplasty Market, 2008-2017
Exhibit 3-90: Total EU Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-91: United Kingdom: Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-92: France: Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-93: Germany: Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-94: Italy: Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-95: EU Market for Computer Assisted Image Guided Surgery Products, 2008-2017
Exhibit 3-96: United Kingdom: Image Guided Surgery Market, 2008-2017
Exhibit 3-97: France: Image Guided Surgery Market, 2008-2017
Exhibit 3-98: Germany: Image Guided Surgery Market, 2008-2017
Exhibit 3-99: Italy: Image Guided Surgery Market, 2008-2017
Exhibit 3-100: Asia-Pacific: Total Spine Surgery Market, 2008-2017
Exhibit 3-101: Asia-Pacific: Total Spine Surgery Market, 2008-2017
Exhibit 3-102: Asia-Pacific: Spine Surgery Market Shares, 2008
Exhibit 3-103: Asia-Pacific: Spinal Fusion and Fixation Market, 2008-2017
Exhibit 3-104: Asia-Pacific: Spinal Fusion and Fixation Market, 2008-2017
Exhibit 3-105: Asia-Pacific: Non-fusion Products Market, 2008-2017
Exhibit 3-106: Asia-Pacific: Non-fusion Products Market, 2008-2017
Exhibit 3-107: Asia-Pacific: Spinal Fusion vs. Non Fusion Markets, 2008 vs. 2017
Exhibit 3-108: Asia-Pacific: Total Disc Replacement Market, 2008-2017
Exhibit 3-109: Asia-Pacific: Total Disc Replacement Market, 2008-2017
Exhibit 3-110: Asia-Pacific: Nucleus Replacement Market, 2008-2017
Exhibit 3-111: Asia-Pacific: Nucleus Replacement Market, 2008-2017
Exhibit 3-112: Asia-Pacific: Interspinous Processes Market, 2008-2017
Exhibit 3-113: Asia-Pacific: Interspinous Processes Market, 2008-2017
Exhibit 3-114: Asia-Pacific: Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-115: Asia-Pacific: Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-116: Asia-Pacific: Image Guided Surgery Market, 2008-2017
Exhibit 3-117: Asia-Pacific: Image Guided Surgery Market, 2008-2017
Exhibit 3-118: Rest of World Spine Surgery Market Shares, 2008
Exhibit 3-119: ROW, Spine Surgery Markets, 2008-2017
Exhibit 3-120: ROW, Spine Surgery Markets, 2008-2017
Exhibit 3-121: ROW: Fusion and Fixation Market, 2008-2017
Exhibit 3-122: ROW: Fusion and Fixation Market, 2008-2017
Exhibit 3-123: ROW: Non-Fusion Market, 2008-2017
Exhibit 3-124: ROW: Total Disc Replacement Market, 2008-2017
Exhibit 3-125: ROW: Nucleus Replacement Market, 2008-2017
Exhibit 3-126: ROW: Interspinous Process Spacers Market, 2008-2017
Exhibit 3-127: ROW: Vertebroplasty/Kyphoplasty Market, 2008-2017
Exhibit 3-128: ROW: Image-Guided Surgery Market, 2008-2017

Exhibit 4-1: CPT spinal fusion codes now allowed by CMS
Exhibit 4-2: BCBSNC coverage of bone morphogenetic protein
Exhibit 4-3: New CMS codes for spinal motion preservation
Exhibit 4-4: Summary of CMS Medicare cost data

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Spine Surgery Worldwide 2008-2017: Products, Technologies, Markets and Opportunities

This report details the complete range of products and technologies in spine surgery, including the surgical management of spine disorders, diseases and trauma, with treatments including use of grafts, demineralized bone, fusion, stabilization, disc replacement, nucleus replacement, vertebroplasty, kyphoplasty, imaging, minimally invasive surgical technologies, energy-based therapies and biologics. The report details current clinical and technology developments in the huge and rapidly growing spine surgery technologies worldwide market, with data on products in development and on the market; market size and forecast; competitor market shares; competitor profiles; and market opportunity.

This report is a detailed market and technology assessment and forecast of the products and technologies in the management of diseases and disorders of the spine. The report describes diseases and disorders of the spine, encompassing congenital disorders, inflammatory and infectious diseases; degenerative diseases; herniations, stenoses, myelopathies and other “mechanical” disorders of the spine; spinal trauma; tumors of the spine; and others. The report characterizes the patient populations, their current clinical management, and trends in clinical management as new techniques and technologies are expected to be developed and emerge. The report details the currently available products and technologies, and manufacturer offerings. The report details products and technologies under development and markets for each in spine surgery. The report provides a current and forecast assessment of the worldwide markets for these technologies, with geographic segmentation by U.S. & Canada, European Union (detailing France, United Kingdom, Germany, Italy and Spain), Japan and Rest of World. The report provides emphasis on the market impact of new technologies through the coming decade, profiling nearly 100 active companies in this industry, with comprehensive detail on key companies, providing data on their current products, current market position and products under development.

Table of Contents:

Executive Summary
Non-fusion products
Disc arthroplasty (total disc replacement)
Nuclear arthroplasty
European Union
Asia-Pacific
Rest of World
Selected company-related events
Medtronic
LDR Spine
Synthes Spine
Disc Motion Technologies
Spine Structure
Products and technologies
CMS, carriers reverse decision on artificial discs
Cost effectiveness

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This report details the complete range of sealants & glues technologies used in traumatic, surgical and other wound closure, from tapes, sutures and staples to hemostats, fibrin sealants/glues and medical adhesives. The report details current clinical and technology developments in this huge and rapidly growing worldwide market, with data on products in development and on the market; market size and forecast; competitor market shares; competitor profiles; and market opportunity.

This report is a market and technology assessment and forecast of surgical sealants, glues, hemostasis, other wound closure and anti-adhesion. The report details the current and emerging products, technologies and markets involved in wound closure and sealing using sutures and staples, tapes, hemostats, fibrin and sealant products, medical adhesives and products to prevent surgical adhesions. The report provides a worldwide current and annual forecast to 2013 of the markets for these technologies, with particular emphasis on the market impact of new technologies through the coming decade. The report provides specific forecasts and shares of the worldwide market by segment for the U.S., Europe (United Kingdom, German, France, Italy, BeNeLux), Latin America, Japan and Rest of World.

The report provides background data on the surgical, disease and traumatic wound patient populations targeted by current technologies and those under development, and the current clinical practices in the management of these patients, including the dynamics among the various clinical specialties or subspecialties vying for patient population and facilitating or limiting the growth of technologies.

The report establishes the current worldwide market size for major technology segments as a baseline for and projecting growth in the market over a ten-year forecast. The report also assesses and projects the composition of the market as technologies gain or lose relative market performance over this period.

Table of Contents:

Executive Summary
Introduction
Demographic trends
Consumer-Driven Product Selection
Mechanisms of Tissue Repair
Commercial Imperatives
Industry Consolidation
Clinical Caseload
Market Segmentation and Dynamics
New Surgical Techniques Drive Market Opportunity
The Uses of Adjunctive Surgical Closure and Securement Products
Product Development History
Evolution of Commercial Markets for Sealants and Adhesives
Company Strategies — Overview

Section 1:          CLINICAL NEED, CASELOAD, AND PROCEDURE VOLUME
1.1         Anatomy and Physiology of Tissue Repair
1.2         The Skin
1.3         Internal Tissues and Organs
1.4         Wound Classification and Types
1.4.1         Classification by Morphology and Severity
1.4.2         Wound Classification by Cause
1.4.3         Surgical Wounds
1.5         Caseload
1.5.1         Cardiovascular
1.5.1.1         Coronary Heart Disease
1.5.1.2         Dysfunctional Heart Valves
1.5.1.3         Peripheral Vascular Disorders
1.5.1.4         Abnormal Aortic Aneurysms
1.5.1.5         Drivers of Caseloads for Cardiac Surgery
1.5.2         Neurological
1.5.2.1         Stroke
1.5.2.2         Parkinson’s Disease
1.5.2.3         Epilepsy
1.5.2.4         Traumatic Injury
1.5.2.5         Peripheral Nerve Treatment
1.5.2.6         Neurology Drivers
1.5.3         Orthopedic
1.5.3.1         Hip Replacements
1.5.3.2         Knee Replacements
1.5.3.3         Cartilage Repair
1.5.3.4         Ligament Damage
1.5.3.5         Bone Grafting
1.5.3.6         Vertebral Disc Repair
1.5.3.7         Drivers of Orthopedic Surgery
1.5.4         Urological
1.5.4.1         Incontinence
1.5.4.2         Drivers of Urological Surgery
1.5.5         Skin
1.5.5.1         Burns
1.5.5.2         Pressure Ulcers
1.5.5.3         Diabetic Ulcers
1.5.5.4         Venous Ulcers
1.5.5.5         Plastic Surgery
1.6         The Role of Modern Sealant, Securement and Hemostatic Products in Surgery
1.6.1         Fibrin Sealants
1.6.2         High-Strength Glues

Section 2:          SCIENCE, TECHNOLOGY, DEVELOPMENT, CLINICAL AND REGULATORY CHALLENGES
2.1         Tissue Healing
2.1.1         Hemostasis
2.1.2         Proliferation and Maturation
2.1.3         Factors That Affect Healing
2.2         Product Development
2.3         Development Timelines
2.3.1         Collagen and Thrombin Combination
2.3.2         Polyethylene Glycol Polymer (PEG)
2.3.3         Albumin Cross-Linked with Glutaraldehyde
2.3.4         Delivery Systems
2.4         Cost Effectiveness
2.5         Regulatory Challenges
2.5.1         Approval Processes
2.5.2         History of Product Development
2.5.3         Regulatory Aspects

Section 3:          PRODUCTS, TECHNOLOGIES, AND FORECAST OPPORTUNITY
3.1         Overview
3.2         Development Timeline
3.3         Sutures, Staples, and Other Mechanical Closure Devices
3.3.1         Competitors and Products
3.3.2         Suppliers
3.3.3         Product Development
3.3.4         Market Analysis and Forecast
3.4         Tapes
3.4.1         Competitors and Products
3.4.2         Products in Development
3.4.3         Market Analysis and Forecast
3.5         Hemostats
3.5.1         Competitors and Products
3.5.2         Products in Development
3.5.3         Market Analysis and Forecasts
3.6         Fibrin and Other Sealant Products
3.6.1         Competitors and Products
3.6.2         Products in Development
3.6.3         Fibrin and Sealant Market and Competitive Activity
3.7         High-Strength Medical Adhesives
3.7.1         Competitors and Products
3.7.2         Products in Development
3.7.3         Market Analysis and Forecasts
3.8         Post-Surgical Adhesion Prevention
3.8.1         Competitors and Products
3.8.2         Products in Development
3.8.3         Market Analysis and Forecasts
3.9         Wound Closure and Securement Markets: Global and Regional Analysis
3.9.1         Americas
3.9.1.1         United States
3.9.1.2         Latin America
3.9.2         Japan
3.9.3         Europe
3.9.4         Rest of World
3.10       Worldwide Markets By Country and Segment

Section 4:          Company Profiles
4.1 3DM, Inc. (3D-Matrix, Ltd.)
4.2 3M
4.3 Abbott Vascular
4.4 AccessClosure, Inc.
4.5 Adhezion Biomedical, LLC
4.6 Advanced Medical Solutions plc
4.7 Allerderm
4.8 Angiotech Pharmaceuticals, Inc.
4.9 Anika Therapeutics, Inc.
4.10 ARC Pharmaceuticals
4.11 Arch Therapeutics, Inc.
4.12 ArthroCare Corporation
4.13 Aso LLC
4.14 Aspen Surgical Products
4.15 Atrax Medical Group
4.16 Avery Dennison
4.17 B. Braun Melsungen AG
4.18 Bastos Viegas, s.a.
4.19 Baxter International Inc.
4.20 Bayer HealthCare
4.21 BD (Becton, Dickinson and Company)
4.22 Berlin Heart GmbH
4.23 Bernsco Surgical Supply
4.24 Biocoral Inc.
4.25 BioCore Medical Technologies, Inc.
4.26 Biogentis, Inc.
4.27 Biomet Inc.
4.28 BIOSTER a.s.
4.29 BioSyntech Canada Inc.
4.30 BSN Medical
4.31 C.R. Bard
4.32 Cardiovascular Sciences, Inc.
4.33 Carl Auffarth GmbH & Co. KG
4.34 Cardiva Medical, Inc.
4.35 Ceremed, Inc.
4.36 Chemence Ltd.
4.37 Chemopharma, s.a.
4.38 Cohera Medical, Inc.
4.39 Collagen Matrix, Inc.
4.40 Coloplast A/S
4.41 ConvaTec
4.42 Covidien Ltd.
4.43 CryoLife Inc.
4.44 CSIRO PhotoMedical Technologies
4.45 CSL Behring
4.46 CSMG Technologies, Inc.
4.47 CuraMedical BV
4.48 Cypress Medical Products
4.49 Derma Sciences, Inc.
4.50 Distrex Ibérica S.A.
4.51 DuPont Applied BioSciences
4.52 Entegrion, Inc.
4.53 FibroGen, Inc.
4.54 Fidia Advanced Biopolymers
4.55 Flamel Technologies SA
4.56 Forticell Bioscience
4.57 FzioMed Inc.
4.58 Gelita Medical BV
4.59 GEM srl
4.60 Genzyme Biosurgery Inc.
4.61 GluStitch, Inc.
4.62 Graceduty Company Limited
4.63 GramsMed, LLC
4.64 Haemacure Corporation
4.65 HAPTO Biotech Israel Ltd.
4.66 Hartmann Group
4.67 Harvest Technologies Corporation
4.68 HemCon Medical Technologies, Inc.
4.69 Hemostasis, LLC
4.70 HyperBranch Medical Technology, Inc.
4.71 Incisive Surgical, Inc.
4.72 Innovasa Corporation
4.73 Integra Lifesciences Corporation
4.74 I-Therapeutix, Inc.
4.75 Johnson & Johnson
4.76 Kaketsuken (Chemo-Sero-Therapeutic Research Institute)
4.77 Kensey Nash Corporation
4.78 Kimberly-Clark Health Care
4.79 Kinetic Concepts, Inc.
4.80 King Pharmaceuticals, Inc.
4.81 Kookbo Chemicals Co., Ltd. (KB Chem.)
4.82 Laboratoires Urgo (Urgo Medical)
4.83 Lewis Medical Supplies
4.84 LifeBond Ltd.
4.85 Lifecore Biomedical, Inc.
4.86 Lohmann & Rauscher
4.87 Marine Polymer Technologies
4.88 Medafor, Inc.
4.89 Medi Surgichem Pvt. Ltd.
4.90 MedTrade Products, Ltd.
4.91 Meyer-Haake GmbH Medical Innovations
4.92 Mölnlycke Health Care AB
4.93 Morris Innovative
4.94 Motex Healthcare Corp.
4.95 Myco Medical
4.96 NeatStitch Ltd.
4.97 Neose Technologies Inc. (Novo Nordisk)
4.98 Nycomed
4.99 Omrix Biopharmaceuticals Inc.
4.100 Pac-Kit Safety Equipment
4.101 Pfizer Inc.
4.102 Pharming Group NV
4.103 Plasma Technologies, Inc.
4.104 PlasmaSeal
4.105 Pluromed, Inc.
4.106 Polyganics
4.107 Polyheal Ltd.
4.108 ProFibrix BV
4.109 Progressive Surgical, Ltd.
4.110 Protein Polymer Technologies, Inc.
4.111 Radi Medical Systems AB
4.112 Resorba Wundversorgung GmbH & Co. KG
4.113 Scapa Group plc
4.114 Scion Cardio-Vascular, Inc.
4.115 Sea Run Holdings
4.116 Seton
4.117 Smith & Nephew plc
4.118 Starch Medical, Inc.
4.119 Stereoplast Ltd.
4.120 Sutura, Inc.
4.121 Synovis Life Technologies
4.122 SyntheMed, Inc.
4.123 Teleflex Medical
4.124 ThermoGenesis Corporation
4.125 Therus Corporation
4.126 Thrombotargets Corp.
4.127 Tissuemed Ltd.
4.128 TraumaCure, Inc.
4.129 TyRx Pharma Inc.
4.130 Vascular Solutions, Inc.
4.131 Vectura Group plc
4.132 Vivostat A/S
4.133 Z-Medica Corporation
4.134 Zimmer
4.135 ZymoGenetics, Inc.
APPENDIX: LIST OF COMPANIES

List of Exhibits
Exhibit ES-1: Recent Acquisitions in the Securement Segment
Exhibit ES-2: Introducers of New Securement Technologies to the U.S. Market
Exhibit ES-3: Definition of Surgical Closure and Securement Products
Exhibit ES-4: Incidence of Two Example Surgical Procedures with High Requirement for Adjunctive Products for Surgical Closure and Securement
Exhibit ES-5: U.S. FDA Approved Uses of Sealants, Glues, and Hemostats
Exhibit ES-6: Synthetic and Biological Sealant Competitors (Non-Fibrin Sealants)
Exhibit ES-7: Selected High-Strength Adhesive Companies and Their Strategies
Exhibit ES-8: Selected Sealant Product Companies and Their Strategies
Exhibit ES-9: Worldwide Growth in the Securement and Closure Market, 2006–2013

Exhibit 1-1: Skin Structure Illustrating Major Organelles and Skin Layers
Exhibit 1-2: Classification of Wounds by Morphology
Exhibit 1-3: Severity Classification of Wounds
Exhibit 1-4: Wound Classification by Etiology
Exhibit 1-5: Prevalence of Different Wound Types, 2008
Exhibit 1-6: Criteria for Adjunctive Use of Hemostats, Sealants, Glues and Adhesion Prevention Products in Surgery
Exhibit 1-7: Surgical Procedures with Potential for the Use of Hemostats, Sealants, Glues and Adhesion Prevention Products, Worldwide
Exhibit 1-8: Potential for Cardiovascular Applications, Prevalence of Applicable Surgical Applications
Exhibit 1-9: Potential for Neurological Applications, Prevalence of Applicable Disorders
Exhibit 1-10: Potential for Orthopedic Applications, Frequency of Major Surgical Interventions
Exhibit 1-11: Potential for Urological Applications, Prevalence of Applicable Disorders
Exhibit 1-12: Potential for Dermal Repair, Prevalence of Applicable Disorders
Exhibit 1-13: Applications of Fibrin and Other Sealants
Exhibit 1-14: Surgical Procedures Using Fibrin and Other Sealant Products (2009–2013)
Exhibit 1-15: Surgical Indications for High-Strength Glues (Europe, 2008)

Exhibit 2-1:  Factors That Affect Wound Healing
Exhibit 2-2: Timescales for Development of Closure and Sealant Products
Exhibit 2-3:  Variables Associated With Clinical Evaluation of Closure and Securement and Related Products

Exhibit 3-1: Manufacturers of Surgical Sutures, Staples, Clips, and Other Mechanical Closure Devices
Exhibit 3-2: Worldwide Sutures and Staples Market Forecast, 2009–2013
Exhibit 3-3: Worldwide Suture and Staples Market 2007, Share by Supplier
Exhibit 3-4: Companies Commercializing First Aid Technologies Often Used as Tapes for Closure
Exhibit 3-5: Worldwide Tapes Market Forecast, 2009-2013
Exhibit 3-6: Worldwide Tapes for Closure Market Share, 2007, by Supplier
Exhibit 3-7: Companies Commercializing Technologies in the Hemostat Category
Exhibit 3-8: Worldwide Hemostats Market Forecast, 2009–2013
Exhibit 3-9: Worldwide Hemostats Market Share, 2007, by Supplier
Exhibit 3-10: Companies Commercializing Technologies in the Sealants Category
Exhibit 3-11: Worldwide Sealants Market Forecast, 2009-2013
Exhibit 3-12: Worldwide Sealants Market Share, 2007, by Supplier
Exhibit 3-13: Companies Commercializing Cyanoacrylate-based High-Strength Medical Adhesives
Exhibit 3-14: Worldwide High-Strength Glues Market Forecast, 2009–2013
Exhibit 3-15: Worldwide High-Strength Glues Market Share 2007, by Supplier
Exhibit 3-16: Companies Commercializing Technologies in the Post-Surgical Adhesion Prevention Category
Exhibit 3-17: Worldwide Post-Operative Adhesion Prevention Market Forecast, 2009–2013
Exhibit 3-18: Worldwide Post Operative Adhesion Prevention Market Share, 2007, by Supplier
Exhibit 3-19:  Size and Growth of Wound Closure and Securement Market, World and Selected Countries, 2007
Exhibit 3-20: Wound Closure Market 2007, by Product Segments: The Major American Countries
Exhibit 3-21: Wound Closure Market 2007, by Product Segments: Japan
Exhibit 3-22: Wound Closure Market 2007, by Product Segments: Major European Countries
Exhibit 3-23: Wound Closure Market 2007, by Product Segments: Rest of World
Exhibit 3-24: Growth Forecast for Closure and Securement Market, 2009–2013

Exhibit 4-1: 3M, Selected Financial Data for 2007
Exhibit 4-2: Abbott Laboratories, Selected Financial Data for the First Nine Months of 2008
Exhibit 4-3: Advanced Medical Solutions’ Selected Financial Data for 2006 and 2007
Exhibit 4-4: Angiotech Pharmaceuticals’ Statement of Income for 2nd Quarter, 2008 (Ending June 30)
Exhibit 4-5: Anika Therapeutics’ Financial Results for 2006 and 2007
Exhibit 4-6: ArthroCare Corporation Financial Data
Exhibit 4-7: B. Braun Financial Data
Exhibit 4-8: Baxter International Financial Data
Exhibit 4-9: C.R. Bard, Inc. Financial Data for Nine Months Ending Sept. 30
Exhibit 4-10: Cardiovascular Sciences, Inc. Financial Data
Exhibit 4-11: Covidien, Selected Financial Data, 2007
Exhibit 4-12: CryoLife Financial Results, 2006 and 2007
Exhibit 4-13: Haemacure Corporation, Selected Financial Data
Exhibit 4-14: Integra Lifesciences, Financial Data
Exhibit 4-15: Johnson & Johnson Key Financial Data, 2006 and 2007
Exhibit 4-16: Kimberly-Clark Health Care Financial Data
Exhibit 4-17: King Pharmaceuticals Financial Data
Exhibit 4-18: Overview of Omrix’ Biosurgical Product Pipeline
Exhibit 4-19: Omrix Biopharmaceuticals Financial Data
Exhibit 4-20: Pfizer Financial Data for 2007 and 2006
Exhibit 4-21: Pharming Financial Data
Exhibit 4-22: Teleflex Inc. Financial Data
Exhibit 4-23: Vascular Solutions Financial Results
Exhibit 4-24: ZymoGenetics Financial Data, 3rd Quarter, 2008

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Market Potential for Hospital Services, Pharmaceuticals and Medical Devices in US

The US, with its healthcare spending crossing US$ 2.2 Trillion in 2007, represents the most important healthcare product and services market in the world. And according to “Market Potential for Hospital Services, Pharmaceuticals and Medical Devices in US”, the new research report, the potential and opportunities in this market are expected to increase several fold in the next five years.

This report provides factual insight supplemented with statistical overview on the past, present and future market. It studies the entire structure, composition and working of the US healthcare sector and describes the potential of hospital services, pharmaceuticals and medical devices in the market. This report discusses the demand, market size and future prospects of nearly every major sector, like cardiovascular, diabetes, musculoskeletal, oncology, wound care management, cosmetic surgery, dental health, and in vitro diagnostics, in the US healthcare market. It identifies key opportunities and roadblocks that will affect the future direction of the market.

“Market Potential for Hospital Services, Pharmaceuticals and Medical Devices in US” thus serves as a guide for healthcare service providers/drug manufactures/investors who are planning to enter the US healthcare market as it helps in identifying and analyzing market opportunities that will suit their business needs and profiles.

Key Findings of the Report

 Total healthcare spending in the US is expected to grow at a CAGR of 7% between 2007 and 2012.
Around 43 Million people are expected to be above 65 years of age in the US by 2012, thereby increasing the prevalence of several chronic diseases.
Around 122 Million Americans are expected to suffer from cardiovascular diseases by 2012, leading to direct expenses of over US$ 414 Billion.
The US, with over 19 Million diabetics by 2012, is expected to fuel the growth of the diabetes drugs and monitoring devices market.
Driven by target-based therapies with negligible side effects, the US oncology market is amongst the fastest growing sectors in the healthcare industry.
The aging baby boomers, coupled with an increasing incidence of hip and knee fractures, are expected to strongly drive the musckoskeletal market.
Driven by a need to look young and attractive, both surgical and non-surgical cosmetic procedures are becoming highly popular.
 
Key Issues & Facts Analyzed in the Report

Evaluation of past, current and future market trends.
Market evaluation by type of disease.
Discussion on the major drivers of the healthcare market.
Identification and evaluation of the opportunities created by the market.
Analysis of major challenges for the market.
Research Methodology Used in the Report

Information Sources
Information has been sourced from books, newspapers, trade journals, white papers, industry portals, government agencies, trade associations, monitoring industry news and developments, and through access to over 3000 paid databases.

Analysis Methods
This industry forecast and analysis is based on various macro- and microeconomic factors, sector and industry specific databases, and our in-house statistical and analytical model. This model takes into account the past and current trends in an economy, and more specifically in an industry, to bring out an objective market analysis.

Our industry experts study the relationship between various industry and economic variables to ensure the required accuracy and desired check on the quality of data and information given in the report.

Table of Contents:

1. Analyst View
2. The US Healthcare Industry
2.1 Source of Funding
2.1.1 Public Coverage
2.1.2 Private Coverage
2.2 Healthcare Outlay
3. What Makes the Market Lucrative?
3.1 High Expenditure on Healthcare
3.2 Aging Population
3.3 Increasing Obesity
3.4 Technological Advancements
4. Healthcare Indicators & Demographics
4.1 Population & Demographics
4.2 Hospitals & Healthcare Professionals
4.3 Mortality & Leading Causes of Death
5. Analysis by Type of Disease To 2012
5.1 Cardiovascular
5.1.1 Facts & Figures
5.1.2 Market Analysis
5.2 Diabetes
5.2.1 Facts & Figures
5.2.2 Market Analysis
5.3 Oncology
5.3.1 Facts & Figures
5.3.2 Market Analysis
5.4 Musckoloskeletal Market
5.4.1 Facts & Figures
5.4.2 Market Analysis
5.5 Wound Care Management
5.5.1 Facts & Figures
5.5.2 Market Analysis
5.6 Cosmetic Surgery
5.6.1 Facts & Figures
5.6.2 Market Analysis
5.7 HIV
5.7.1 Facts & Figures
5.7.2 Market Analysis
5.8 Dental Health
5.8.1 Facts & Figures
5.8.2 Market Analysis
5.9 IVD
5.9.1 Market Analysis
6. Industry Roadblocks
6.1 Stringent Regulations
6.2 Large Uninsured Population
6.3 Medical Tourism

List of Figures:

Figure 2-1: US - Healthcare Expenditure (in Billion US$), 2001-2007E
Figure 2-2: US - Forecast for Healthcare Expenditure (in Billion US$), 2008-2012
Figure 2-3: US - Healthcare Expenditure by Source of Funding (%), 2006
Figure 2-4: US - Healthcare Expenditure by Type of Service (%), 2006
Figure 3-1: US - Population Aged 65 Years & Above (in Million), 2001-2007 & 2012F
Figure 3-2: US - Number of Baby-boomers Living with Chronic Conditions (in Million), 2000, 2010F & 2020F
Figure 3-3: US - Annual Healthcare Cost per Person by Number of Chronic Conditions (in US$)
Figure 3-4: US - Prevalence of Obesity* among Adults** (%), 1995, 2000, 2005 & 2012F
Figure 4-1: US - Population (in Million), 2001-2007
Figure 4-2: US - Forecast for Population (in Million), 2008*-2012
Figure 4-3: US - Population Breakup by Age Group (%), 2001-2007
Figure 4-4: US - Forecast for Population Breakup by Age Group (%), 2008*-2012
Figure 4-5: US - Number of Community Hospitals (1981, 1991, 2001 & 2006)
Figure 4-6: US - Hospital Admissions by Boomers & Non-boomers (in Million), 2004, 2010F, 2020F & 2030F
Figure 4-7: US - Physician Office Visits by Boomers & Non-boomers (in Million), 2004, 2010F, 2020F & 2030F
Figure 4-8: US - Hospital Admissions by Age (%), 2004 & 2030F
Figure 4-9: US - Hospital Revenues by Inpatients & Outpatients (%), 1981, 1991, 2001 & 2005
Figure 4-10: US - Hospital Surgeries by Inpatients & Outpatients (%), 1981, 1991, 2001 & 2005
Figure 4-11: US - Share of Healthcare Employment in Total Employment (%), 2006
Figure 4-12: US - Number of Doctors (1990, 1995, 2000 & 2003 to 2007E)
Figure 4-13: US - Number of Dentists (1990, 1995, 2000 & 2003 to 2007E)
Figure 4-14: US - Number of Nurses (1990, 1995, 2000 & 2003 to 2007E)
Figure 4-15: US - Supply & Demand of Primary Care Physicians* (in ‘000), 2000, 2005, 2010F, 2015F & 2020F
Figure 4-16: US - Shortage of Specialists* (in ‘000), 2005, 2010F, 2015F & 2020F
Figure 4-17: US - Breakup of Leading Causes of Death (%), 2005
Figure 4-18: US - Number of Deaths due to Leading Causes (in ‘000), 2005
Figure 4-19: US - Forecast for Breakup of Leading Causes of Death (%), 2030
Figure 4-20: US - Forecast for Number of Deaths due to Leading Causes (in ‘000), 2030
Figure 5-1: US - Deaths by Type of Cardiovascular Disease (%), 2004
Figure 5-2: US - Diabetic Patients* (in ‘000), 2003. 2007E, 2012F & 2025F
Figure 5-3: US - Diabetes Drug Market (in Billion US$), 2000-2007E & 2012F
Figure 5-4: US - Breakup of OADs & Insulin in Diabetes Drug Market (%), 2000-2007E & 2012F
Figure 5-5: US - Insulin Market (in Billion US$), 2000-2007E & 2012F
Figure 5-6: US - Insulin Delivery Market (in Billion US$), 2004, 2007E & 2012F
Figure 5-7: US - Insulin Delivery Market by Type of Device (%), 2004
Figure 5-8: US - Oral Anti-diabetic Market (in Billion US$), 2000-2007E & 2012F
Figure 5-9: US - Blood Glucose Testing Market (in Billion US$), 2004, 2007E & 2012F
Figure 5-10: US - Blood Glucose Testing Market by Type of Product (%), 2004
Figure 5-11: US - Estimated Number of New Cancer Cases (2005, 2008 & 2012)
Figure 5-12: US - Cancer Market (in Billion US$), 1999, 2004, 2007E & 2012F
Figure 5-13: US - Breakup of Cancer Market by Therapy (%), 1999, 2004, 2007E & 2012F
Figure 5-14: US - Chemotherapy Market (in Billion US$), 1999, 2004, 2007E & 2012F
Figure 5-15: US - Cancer Surgery Market (in Billion US$), 1999, 2004, 2007E & 2012F
Figure 5-16: US - Radiation Therapy Market (in Billion US$), 1999, 2004, 2007E & 2012F
Figure 5-17: US - Biotechnology-based Cancer Drug Market (in Billion US$), 1999, 2004, 2007E & 2012F
Figure 5-18: US - Cancer Diagnostic Market (in Billion US$), 2006 & 2012F
Figure 5-19: US - Osteoporosis & Low Bone Mass Patients (in Million), 2007, 2010F & 2020F
Figure 5-20: US - Osteoporosis-related Fractures per Annum (%)
Figure 5-21: US - Knee Replacement Procedures* (in Number), 2000-2007E & 2012F
Figure 5-22: US - Hip Replacement Procedures* (in Number), 2000-2007E & 2012F
Figure 5-23: US - Musculoskeletal Device & Implant Market (in Billion US$), 2002, 2004, 2005, 2008F & 2012F
Figure 5-24: US - Musculoskeletal Device & Implant Market by Segment (%), 2008
Figure 5-25: US - Orthopedic Reconstructive Device Market by Segment (%), 2008
Figure 5-26: US - Fixation Market by Segment (%), 2008
Figure 5-27: US - Spinal Product Market by Segment (%), 2008
Figure 5-28: US - Number of Wounds & Wounds Treated with Active & Advanced Wound Care Products (in Million), 2005
Figure 5-29: US - Wound Care Product Market (in Million US$), 2001, 2003, 2005E, 2007E, 2009F & 2012F
Figure 5-30: US - Surgical & Non-surgical Cosmetic Procedures (in ‘000), 1997 & 2004-2007
Figure 5-31: US - Federal Expenditure on HIV/AIDS (in Billion US$), 2006-2009F
Figure 5-32: US - Forecast for Breakup of Federal Expenditure on HIV/AIDS (%), 2009
Figure 5-33: US - Antiretroviral Market Dynamics (in ‘000)
Figure 5-34: US - Antiretroviral Market (in Billion US$), 2004, 2007E & 2012F
Figure 5-35: US - Share of Key Players in Antiretroviral Market (%), 2004
Figure 5-36: US - Expenditure on Dental Services (in Million US$), 2000-2007E & 2012F
Figure 5-37: US - IVD Market (in Billion US$), 2006 & 2007E
Figure 5-38: US - IVD Market* by Segment (%), 2007E
Figure 5-39: US - Forecast for IVD Market (in Billion US$), 2008-2012
Figure 6-1: US - Uninsured People (in Million), 2005-2007E

List of Tables:

Table 2-1: US - Public Healthcare Expenditure by Source of Funding (in Million US$), 2001-2006
Table 2-2: US - Private Healthcare Expenditure by Source of Funding (in Million US$), 2001-2006
Table 2-3: US - Healthcare Expenditure by Type of Service (in Billion US$), 2001-2006
Table 3-1: US - Healthcare Expenditure (in Billion US$) & Healthcare Expenditure as a % of GDP w.r.t. Various Developed Countries (2007)
Table 5-1: US - Prevalence of Various Cardiovascular Diseases (in Million), 2002, 2005, 2007E & 2012F
Table 5-2: US - Number of Various Cardiovascular Procedures (2001, 2005 & 2012F)
Table 5-3: US - Cost & In-hospital Death Rates of Various Cardiovascular Procedures (2004)
Table 5-4: US - Cardiovascular Diseases & Stroke Expenditure by Type (in Billion US$), 2008E
Table 5-5: US - Forecast for Cardiovascular Diseases & Stroke Expenditure by Type (in Billion US$), 2012
Table 5-6: US - Diabetic Patients in Age Group of 20-79 Years (in ‘000), 2003
Table 5-7: US - Forecast for Diabetic Patients in Age Group of 20-79 Years (in ‘000), 2025
Table 5-8: US - Estimated Number of New Cancer Cases for Selected Cancer Sites (2008)
Table 5-9: US - Musculoskeletal Device & Implant Market by Segment (in Million US$), 2002, 2004, 2005 & 2008E
Table 5-10: US - Wound Care Product Market by Segment (in Million US$), 2001, 2003, 2005E, 2007E, 2009F & 2010F
Table 5-11: US - Key Facts related to Surgical Cosmetic Procedures
Table 5-12: US - Key Facts related to Non-surgical Cosmetic Procedures
Table 5-13: US - Per Procedure Physician Fees & Expenditure on Various Surgical Cosmetic Procedures (in US$), 2007
Table 5-14: US - Statistics of Various Surgical Cosmetic Procedures (2007)
Table 5-15: US - Per Procedure Physician Fees & Expenditure on Various Non-surgical Cosmetic Procedures (in US$), 2007
Table 5-16: US - Statistics of Various Non-surgical Cosmetic Procedures (2007)
Table 5-17: US - Number of Top 5 Male & Female Cosmetic Procedures (in ‘000), 2007
Table 5-18: US - AIDS Diagnosis & Deaths (in Number), 2002-2006
Table 5-19: US - Dental Equipment & Supplies Market (in Million US$), 1993, 1998, 2003, 2008E & 2013F
Table 5-20: US - Dental Procedures & Visits (in Million), 1993, 1998, 2003, 2008E & 2013F
Table 6-1: US - Cost of Various Surgical Procedures w.r.t. Other Countries (in US$)

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A new report by GlobalData, the business intelligence specialists, finds that increase in advances in technology, the obesity rates, growing patient awareness, and increase in the incidence of cardiovascular diseases are driving growth in the market. GlobalData’s report, “Europe Coronary Stents Market: Revival of Drug Eluting Stents to Drive Growth”, highlights these factors as the key drivers for the Europe coronary stents market.

The Drug Eluting Stent (Des) Segment To Continue Its Growth Trajectory
The DES segment is the largest revenue contributing segment in the European coronary stent market. The DES market in the Europe, valued at $1.3 billion in 2008 is forecast to reach $1.4 billion by the end of 2009. The introduction of DES in 2002 rapidly reshaped the overall cardiovascular devices market in a few short years. Market growth is very strong for DES in Europe due to high adoption rates. The DES market in Europe is mainly driven by factors such as biologically friendly material, long lasting results, and high adoption rates.

Increased Obesity Rates In Some Population Groups Enhances The Demand For Percutaneous Coronary Intervention (Pci)
Increasing obesity rates in some segments of the population is enhancing the demand for efficient PCI. Obesity and overweight levels are increasing rapidly within the European Union (EU). In the year 2007, over three million children in Europe were considered to be obese. Over 25% of European men and 36% of women are considered to be obese. With the increase in patient demand, it is crucial to perform procedures that take less times, are cost effective, and involve reduced hospital stays. PCI procedures involve minimal scarring, quick recovery time, and therefore will be considered as the therapy of choice in revascularization in the near future.

Advanced Coatings Such As Diamond Like Carbon Coating (DLC) To Play a Major Role in the European Coronary Stent Market
DLC is a new type of coating material which means in addition to being sterile and cutting down friction, they do not respond chemically with their environment. The main factors that make this technology promising are durability, resistant to corrosion, bio-compatibility, and haemocompatibility. Current form of DES has one polymer compound sprayed inside the metal stent. Future DES is trying the effectiveness of multiple layers of coat on the outer surface of the stent.

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Asia-Pacific Surgical Equipment Investment Opportunities, Analysis and Forecasts to 2015

Summary

This report is an essential source for in-depth information and data relating to the Asia Pacific surgical equipment market. It also offers detailed and comprehensive coverage of market revenue, volume, distribution and company share information; and the latest news, financial deals and pipeline products information of each of the key sub-segments of the surgical equipment market in the Asia Pacific

Scope

- The report provides surgical equipment devices information broken down into categories in the Asia Pacific.
- Total revenues, products sold and end users.
- Market shares of all the key competitors.
- Key pipeline products that are set to shape the market, broken down by sector.
- Information on the top medical equipment companies in the sector in the country covering business description, strategic analysis, and financial information.
- Healthcare structure, regulatory environment, approval process, pricing trends and reimbursement.
- Product and brand updates, strategy changes, R&D projects, corporate expansions and contractions and regulatory changes.
- Key mergers and acquisitions, partnerships, private equity investments and IPOs.
- Customer, hospitals and physicians data.

Reasons to buy

- Gain a strong understanding of the surgical equipment market in Asia Pacific.
- Evaluate and compare the attractiveness of the market in the region.
- Identify growth segments and opportunities in each industry sector within the region.
- Evaluate the pipeline of key products that will change the sector, and identify threats and opportunities before the products are launched in the region.
- Analyze the competitiveness of the market in the region and identify hotspots.
- Develop strategies based on the latest product, brand, expansion and research and development news in the region.
- Do deals with an understanding of how competitors are financed, and the mergers and partnerships that have shaped the market in the region.
- Identify and analyze the strengths and weaknesses of the industry incumbents in the region.

Table of Contents :

1 Table of Contents 2
1.1 List of Tables 8
1.2 List of Figures 10
2 Introduction 12
2.1 What Is This Report About? 12
3 Definitions of the Markets Covered in the Report 13
3.1 Surgical Equipment 13
3.2 Electrosurgical Devices 13
3.3 Surgical sutures 13
3.4 Hand Instrument 13
4 Surgical Equipment in Asia-Pacific 14
4.1 Surgical Equipment, Asia-Pacific, Overall Revenue ($ mn), 2000-2015 14
4.2 Surgical Equipment, Asia-Pacific, Category Volume (Units), 2000-2015 18
4.3 Surgical Equipment, Asia-Pacific, Company Share (2006-2007) 21
5 Surgical Equipment Cross Country Comparison 22
5.1 Surgical Equipment, Cross Country Comparison, Revenue ($ mn), 2000-2015 22
6 Surgical Equipment In Japan 23
6.1 Surgical Equipment, Japan, Overall Revenue ($ mn), 2000-2015 23
6.2 Surgical Equipment, Japan, Category Volume (Units), 2000-2015 26
6.3 Surgical Equipment, Japan, Distribution Share (2006-2007) 29
6.3.1 Electrosurgical Devices Distribution Share (2006-2007) 29
6.3.2 Hand Instruments Distribution Share (2007-2008) 29
6.3.3 Surgical Sutures Distribution Share (2007-2008) 30
6.4 Surgical Equipment, Japan, Company Share (2006-2007) 31
6.4.1 Surgical Equipment, Japan, Company Share (2006-2007) 31
6.4.2 Electrosurgical Devices, Japan, Company Share (2006-2007) 32
6.4.3 Hand Instruments, Japan, Company Share (2006-2007) 33
6.4.4 Surgical Sutures, Japan, Company Share (2006-2007) 34
7 Surgical Equipment In China 35
7.1 Surgical Equipment, China, Overall Revenue ($ mn), 2000-2015 35
7.2 Surgical Equipment, China, Category Volume (Units), 2000-2015 38
7.3 Surgical Equipment, China, Distribution Share (2006-2007) 41
7.3.1 Electrosurgical Devices Distribution Share (2006-2007) 41
7.3.2 Hand Instruments Distribution Share (2007-2008) 41
7.3.3 Surgical Sutures Distribution Share (2007-2008) 42
7.4 Surgical Equipment, China, Company Share (2006-2007) 43
7.4.1 Surgical Equipment, China, Company Share (2006-2007) 43
7.4.2 Electrosurgical Devices, China, Company Share (2006-2007) 44
7.4.3 Hand Instruments, China, Company Share (2006-2007) 45
7.4.4 Surgical Sutures, China, Company Share (2006-2007) 46
8 Surgical Equipment In Australia 47
8.1 Surgical Equipment, Australia, Overall Revenue ($ mn), 2000-2015 47
8.2 Surgical Equipment, Australia, Category Volume (Units), 2000-2015 50
8.3 Surgical Equipment, Australia, Distribution Share (2006-2007 53
8.3.1 Electrosurgical Devices Distribution Share (2006-2007) 53
8.3.2 Hand Instruments Distribution Share (2007-2008) 53
8.3.3 Surgical Sutures Distribution Share (2007-2008) 54
8.4 Surgical Equipment, Australia, Company Share (2006-2007) 55
8.4.1 Surgical Equipment, Australia, Company Share (2006-2007) 55
8.4.2 Electrosurgical Devices, Australia, Company Share (2006-2007) 56
8.4.3 Hand Instruments, Australia, Company Share (2006-2007) 57
8.4.4 Surgical Sutures, Australia, Company Share (2006-2007) 58
9 Surgical Equipment In India 59
9.1 Surgical Equipment, India, Overall Revenue ($ mn), 2000-2015 59
9.2 Surgical Equipment, India, Category Volume (Units), 2000-2015 62
9.3 Surgical Equipment, India, Distribution Share (2006-2007) 65
9.3.1 Electrosurgical Devices Distribution Share (2006-2007) 65
9.3.2 Hand Instruments Distribution Share (2007-2008) 65
9.3.3 Surgical Sutures Distribution Share (2007-2008) 66
9.4 Surgical Equipment, India, Company Share (2006-2007) 67
9.4.1 Surgical Equipment, India, Company Share (2006-2007) 67
9.4.2 Electrosurgical Devices, India, Company Share (2006-2007) 68
9.4.3 Hand Instruments, India, Company Share (2006-2007) 69
9.4.4 Surgical Sutures, India, Company Share (2006-2007) 70
10 Overview of Key Companies in Asia-Pacific Surgical Equipment Market 71
10.1 Ethicon, Inc. 71
10.1.1 Company Overview 71
10.1.2 Ethicon, Inc. Pipeline Products 71
10.2 Covidien Ltd. 73
10.2.1 Company Overview 73
10.2.2 Value Chain Analysis 74
10.3 B. Braun Melsungen AG 77
10.3.1 Company Overview 77
10.3.2 Value Chain Analysis 77
10.4 CONMED Corporation 81
10.4.1 Company Overview 81
10.4.2 Value Chain Analysis 82
10.4.3 CONMED Corporation Pipeline Products 84
10.5 KLS Martin, L.P. 85
10.5.1 Company Overview 85
10.6 ERBE Elektromedizin GmbH 85
10.6.1 Company Overview 85
10.7 MEDICON eG 85
10.7.1 Company Overview 85
10.8 Sutures India Private Limited 86
10.8.1 Company Overview 86
10.9 CENTENIAL SURGICAL SUTURE LTD. 86
10.9.1 Company Overview 86
10.10 MCo Hospital Aids Pvt. Ltd. 86
10.10.1 Company Overview 86
10.11 Lotus Surgicals Pvt. Ltd. 87
10.11.1 Company Overview 87
10.12 Stericat Gutstrings Pvt. Ltd. 87
10.12.1 Company Overview 87
10.13 Gray Surgical 88
10.13.1 Company Overview 88
10.13.2 Gray Surgical Pipeline Products 88
10.14 Dynek Pty. Ltd. 89
10.14.1 Company Overview 89
10.15 FEATHER Safety Razor Co., Ltd. 89
10.15.1 Company Overview 89
10.16 DB Health 89
10.16.1 Company Overview 89
10.17 Gigaa Optronics Technology Company Ltd. 90
10.17.1 Company Overview 90
10.18 Guilin Kangxing Medical Instrument Co., Ltd. 90
10.18.1 Company Overview 90
10.19 Hangzhou Hawk Optical Electronic Instruments Co., Ltd 90
10.19.1 Company Overview 90
10.20 HBM Piaoan Medical Dressing. Inc 90
10.20.1 Company Overview 90
10.21 Huaian Angel Medical Instuments Co.,Ltd. 91
10.21.1 Company Overview 91
10.22 Huaiyin Medical Instruments Co., Ltd. 91
10.22.1 Company Overview 91
10.23 Jiangsu Dengguan Medical Treatment Instrument Co., Ltd. 91
10.23.1 Company Overview 91
10.24 A.R. Micro Surgicals 92
10.24.1 Company Overview 92
10.25 AARVAM Medical Systems 92
10.25.1 Company Overview 92
10.26 Ademco 93
10.26.1 Company Overview 93
10.27 Alpha Medicare and Devices Ltd. 93
10.27.1 Company Overview 93
10.28 Chatterjee Surgical 93
10.28.1 Company Overview 93
10.29 Futura Surgicare Pvt. Ltd. 94
10.29.1 Company Overview 94
10.30 Hindustan Syringes & Medical Devices Ltd. 94
10.30.1 Company Overview 94
10.31 Hospital Equipment Manufacturing Company 94
10.31.1 Company Overview 94
10.32 Jindal Medical & Scientific Instruments Company (Pvt.) Ltd. 95
10.32.1 Company Overview 95
11 Financial Deals Landscape 96
11.1 Partnerships 96
11.1.1 Stille Signs an Agreement with GE Healthcare 96
11.1.2 MedX Health Enters Into An Agreement With Naimco/Rich-Mar 97
12 Recent Developments 98
12.1 Strategy and Business Planning 98
12.1.1 Apr 29, 2009: Bausch & Lomb Plans to Market Surgical Equipment to Eye Doctors In Japan 98
12.1.2 Apr 26, 2009: Covidien Enters Into Indian Market, Establishes Headquarters At Gurgaon, India 98
12.1.3 Feb 26, 2009: Abbott Opens New Manufacturing Facility In Singapore 98
12.2 Product News 99
12.2.1 Apr 30, 2009: Solta Medical’s Thermage System Receives Chinese Regulatory Approval 99
12.2.2 Feb 23, 2009: Cardima Announces Successful Completion Of Second Training Session In Thailand 99
12.2.3 Jan 07, 2009: Q-Med Has Been Awarded Registration Approval In China For Restylane 99
12.2.4 Oct 28, 2008: Top Indian Cancer Hospital To Introduce Advanced Radiosurgery Treatments With Novalis Tx From Varian Medical Systems And BrainLAB 100
12.2.5 Oct 09, 2008: Covidien Introduces Permacol Biologic Implant 100
13 Appendix 101
13.1 Global Markets Direct Research Methodology 101
13.2 Coverage 102
13.3 Secondary Research 102
13.4 Primary Research 103
13.5 Models 103
13.6 Forecasts 104
13.7 Expert Panel Validation 104
13.8 Currency Conversion 105
13.9 Contact Us 106
13.10 Disclaimer 106

1.1 List of Tables

Table 1: Surgical Equipment, Asia-Pacific, Overall Revenue ($ mn), 2000-2015 14
Table 2: Surgical Equipment, Asia-Pacific, Cross-Category Analysis, 2000-2015 15
Table 3: Surgical Equipment, Asia-Pacific, Overall Revenue ($ mn), Historic, 2000-2008 16
Table 4: Surgical Equipment, Asia-Pacific, Overall Revenue ($ mn), Forecast, 2008-2015 17
Table 5: Surgical Equipment, Asia-Pacific, Category Volume (Units), 2000-2015 18
Table 6: Surgical Equipment, Asia-Pacific, Category Volume (Units), Historic, 2000-2008 19
Table 7: Surgical Equipment, Asia-Pacific, Category Volume (Units), Forecast, 2008-2015 20
Table 8: Surgical Equipment, Asia-Pacific, Company Share by Revenue ($ mn), 2006-2007 21
Table 9: Surgical Equipment, Cross Country Comparison, Revenue ($ mn), 2000-2015 22
Table 10: Surgical Equipment, Japan, Overall Revenue ($ mn), 2000-2015 23
Table 11: Surgical Equipment, Japan, Overall Revenue ($ mn), Historic, 2000-2008 24
Table 12: Surgical Equipment, Japan, Overall Revenue ($ mn), Forecast, 2008-2015 25
Table 13: Surgical Equipment, Japan, Category Volume (Units), 2000-2015 26
Table 14: Surgical Equipment, Japan, Category Volume (Units), Historic, 2000-2008 27
Table 15: Surgical Equipment, Japan, Category Volume (Units), Forecast, 2008-2015 28
Table 16: Electrosurgical Devices, Japan, Distribution Share by Revenue ($mn), 2007-2008 29
Table 17: Hand Instruments, Japan, Distribution Share by Revenue ($mn), 2007-2008 29
Table 18: Surgical Sutures, Japan, Distribution Share by Revenue ($mn), 2007-2008 30
Table 19: Surgical Equipment, Japan, Company Share by Revenue ($ mn), 2006-2007 31
Table 20: Electrosurgical Devices, Japan, Company Share by Revenue ($ mn), 2006-2007 32
Table 21: Hand Instruments, Japan, Company Share by Revenue ($ mn), 2006-2007 33
Table 22: Surgical Sutures, Japan, Company Share by Revenue ($ mn), 2006-2007 34
Table 23: Surgical Equipment, China, Overall Revenue ($ mn), 2000-2015 35
Table 24: Surgical Equipment, China, Overall Revenue ($ mn), Historic, 2000-2008 36
Table 25: Surgical Equipment, China, Overall Revenue ($ mn), Forecast, 2008-2015 37
Table 26: Surgical Equipment, China, Category Volume (Units), 2000-2015 38
Table 27: Surgical Equipment, China, Category Volume (Units), Historic, 2000-2008 39
Table 28: Surgical Equipment, China, Category Volume (Units), Forecast, 2008-2015 40
Table 29: Electrosurgical Devices, China, Distribution Share by Revenue ($mn), 2007-2008 41
Table 30: Hand Instruments, China, Distribution Share by Revenue ($mn), 2007-2008 41
Table 31: Surgical Sutures, China, Distribution Share by Revenue ($mn), 2007-2008 42
Table 32: Surgical Equipment, China, Company Share by Revenue ($ mn), 2006-2007 43
Table 33: Electrosurgical Devices, China, Company Share by Revenue ($ mn), 2006-2007 44
Table 34: Hand Instruments, China, Company Share by Revenue ($ mn), 2006-2007 45
Table 35: Surgical Sutures, China, Company Share by Revenue ($ mn), 2006-2007 46
Table 36: Surgical Equipment, Australia, Overall Revenue ($ mn), 2000-2015 47
Table 37: Surgical Equipment, Australia, Overall Revenue ($ mn), Historic, 2000-2008 48
Table 38: Surgical Equipment, Australia, Overall Revenue ($ mn), Forecast, 2008-2015 49
Table 39: Surgical Equipment, Australia, Category Volume (Units), 2000-2015 50
Table 40: Surgical Equipment, Australia, Category Volume (Units), Historic, 2000-2008 51
Table 41: Surgical Equipment, Australia, Category Volume (Units), Forecast, 2008-2015 52
Table 42: Electrosurgical Devices, Australia, Distribution Share by Revenue ($mn), 2007-2008 53
Table 43: Hand Instruments, Australia, Distribution Share by Revenue ($mn), 2007-2008 53
Table 44: Surgical Sutures, Australia, Distribution Share by Revenue ($mn), 2007-2008 54
Table 45: Surgical Equipment, Australia, Company Share by Revenue ($ mn), 2006-2007 55
Table 46: Electrosurgical Devices, Australia, Company Share by Revenue ($ mn), 2006-2007 56
Table 47: Hand Instruments, Australia, Company Share by Revenue ($ mn), 2006-2007 57
Table 48: Surgical Sutures, Australia, Company Share by Revenue ($ mn), 2006-2007 58
Table 49: Surgical Equipment, India, Overall Revenue ($ mn), 2000-2015 59
Table 50: Surgical Equipment, India, Overall Revenue ($ mn), Historic, 2000-2008 60
Table 51: Surgical Equipment, India, Overall Revenue ($ mn), Forecast, 2008-2015 61
Table 52: Surgical Equipment, India, Category Volume (Units), 2000-2015 62
Table 53: Surgical Equipment, India, Category Volume (Units), Historic, 2000-2008 63
Table 54: Surgical Equipment, India, Category Volume (Units), Forecast, 2008-2015 64
Table 55: Electrosurgical Devices, India, Distribution Share by Revenue ($mn), 2007-2008 65
Table 56: Hand Instruments, India, Distribution Share by Revenue ($mn), 2007-2008 65
Table 57: Surgical Sutures, India, Distribution Share by Revenue ($mn), 2007-2008 66
Table 58: Surgical Equipment, India, Company Share by Revenue ($ mn), 2006-2007 67
Table 59: Electrosurgical Devices, India, Company Share by Revenue ($ mn), 2006-2007 68
Table 60: Hand Instruments, India, Company Share by Revenue ($ mn), 2006-2007 69
Table 61: Surgical Sutures, India, Company Share by Revenue ($ mn), 2006-2007 70
Table 62: Ethicon, Inc. Pipeline Products by Equipment Type 71
Table 63: Ethicon, Inc. Pipeline Products By Development Stage 71
Table 64: Ethicon, Inc. Pipeline Products By Therapy Area 72
Table 65: Ethicon, Inc. Pipeline Products By Clinical Trials 72
Table 66: CONMED Corporation Pipeline Products by Equipment Type 84
Table 67: CONMED Corporation Pipeline Products By Development Stage 84
Table 68: CONMED Corporation Pipeline Products By Therapy Area 84
Table 69: Gray Surgical Pipeline Products by Equipment Type 88
Table 70: Gray Surgical Pipeline Products By Development Stage 88
Table 71: Gray Surgical Pipeline Products By Therapy Area 88
Table 72: Stille Signs An Agreement With GE Healthcare 96
Table 73: MedX Health Enters Into An Agreement With Naimco/Rich-Mar 97
Table 74: USD to Local Currency, Average Exchange Rate 2008 105

1.2 List of Figures

Figure 1: Surgical Equipment, Asia-Pacific, Overall Revenue ($ mn), 2000-2015 14
Figure 2: Surgical Equipment, Asia-Pacific, Cross-Category Analysis, 2000-2015 15
Figure 3: Surgical Equipment, Asia-Pacific, Overall Revenue ($ mn), Historic, 2000-2008 16
Figure 4: Surgical Equipment, Asia-Pacific, Overall Revenue ($ mn), Forecast, 2008-2015 17
Figure 5: Surgical Equipment, Asia-Pacific, Category Volume (Units), 2000-2015 18
Figure 6: Surgical Equipment, Asia-Pacific, Category Volume (Units), Historic, 2000-2008 19
Figure 7: Surgical Equipment, Asia-Pacific, Category Volume (Units), Forecast, 2008-2015 20
Figure 8: Surgical Equipment, Asia-Pacific, Company Share (%), 2007 21
Figure 9: Surgical Equipment, Cross Country Comparison, Revenue ($ mn), 2000-2015 22
Figure 10: Surgical Equipment, Japan, Overall Revenue ($ mn), 2000-2015 23
Figure 11: Surgical Equipment, Japan, Overall Revenue ($ mn), Historic, 2000-2008 24
Figure 12: Surgical Equipment, Japan, Overall Revenue ($ mn), Forecast, 2008-2015 25
Figure 13: Surgical Equipment, Japan, Category Volume (Units), 2000-2015 26
Figure 14: Surgical Equipment, Japan, Category Volume (Units), Historic, 2000-2008 27
Figure 15: Surgical Equipment, Japan, Category Volume (Units), Forecast, 2008-2015 28
Figure 16: Surgical Equipment, Japan, Company Share (%), 2007 31
Figure 17: Electrosurgical Devices, Japan, Company Share (%), 2007 32
Figure 18: Hand Instruments, Japan, Company Share (%), 2007 33
Figure 19: Surgical Sutures, Japan, Company Share (%), 2007 34
Figure 20: Surgical Equipment, China, Overall Revenue ($ mn), 2000-2015 35
Figure 21: Surgical Equipment, China, Overall Revenue ($ mn), Historic, 2000-2008 36
Figure 22: Surgical Equipment, China, Overall Revenue ($ mn), Forecast, 2008-2015 37
Figure 23: Surgical Equipment, China, Category Volume (Units), 2000-2015 38
Figure 24: Surgical Equipment, China, Category Volume (Units), Historic, 2000-2008 39
Figure 25: Surgical Equipment, China, Category Volume (Units), Forecast, 2008-2015 40
Figure 26: Surgical Equipment, China, Company Share (%), 2007 43
Figure 27: Electrosurgical Devices, China, Company Share (%), 2007 44
Figure 28: Hand Instruments, China, Company Share (%), 2007 45
Figure 29: Surgical Sutures, China, Company Share (%), 2007 46
Figure 30: Surgical Equipment, Australia, Overall Revenue ($ mn), 2000-2015 47
Figure 31: Surgical Equipment, Australia, Overall Revenue ($ mn), Historic, 2000-2008 48
Figure 32: Surgical Equipment, Australia, Overall Revenue ($ mn), Forecast, 2008-2015 49
Figure 33: Surgical Equipment, Australia, Category Volume (Units), 2000-2015 50
Figure 34: Surgical Equipment, Australia, Category Volume (Units), Historic, 2000-2008 51
Figure 35: Surgical Equipment, Australia, Category Volume (Units), Forecast, 2008-2015 52
Figure 36: Surgical Equipment, Australia, Company Share (%), 2007 55
Figure 37: Electrosurgical Devices, Australia, Company Share (%), 2007 56
Figure 38: Hand Instruments, Australia, Company Share (%), 2007 57
Figure 39: Surgical Sutures, Australia, Company Share (%), 2007 58
Figure 40: Surgical Equipment, India, Overall Revenue ($ mn), 2000-2015 59
Figure 41: Surgical Equipment, India, Overall Revenue ($ mn), Historic, 2000-2008 60
Figure 42: Surgical Equipment, India, Overall Revenue ($ mn), Forecast, 2008-2015 61
Figure 43: Surgical Equipment, India, Category Volume (Units), 2000-2015 62
Figure 44: Surgical Equipment, India, Category Volume (Units), Historic, 2000-2008 63
Figure 45: Surgical Equipment, India, Category Volume (Units), Forecast, 2008-2015 64
Figure 46: Surgical Equipment, India, Company Share (%), 2007 67
Figure 47: Electrosurgical Devices, India, Company Share (%), 2007 68
Figure 48: Hand Instruments, India, Company Share (%), 2007 69
Figure 49: Surgical Sutures, India, Company Share (%), 2007 70
Figure 50: Covidien Ltd./Tyco Healthcare Value Chain Analysis 74
Figure 51: B. Braun Melsungen AG Value Chain Analysis 77
Figure 52: CONMED Corporation Value Chain Analysis 82
Figure 53: Global Markets Direct Methodology 101

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